Background: Cyclosporine-A (CsA) is an immunosuppressive drug used in organ transplantation. Side effects of CsA such as body weight loss and decreased fertility rate have been reported. Satureja hortensis is a therapeutic plant with antioxidant properties. Materials and Methods: 24 adult male rats weighing 200±20 gr were divided into three groups (n=8): control group which received no treatmen...

Rapid detection of lactate as the major fuel source and material to support level blood sugar can open up a new class analysis for nutritionists sports medicine practitioners. Here, rapid user-friendly method monitoring changes in concentration is reported, involving use paper strip coated with gold nanoparticles (AuNPs). The aqueous extract Satureja hortensis used reduction agent green synthes...

Dichloromethane and methanol extracts of seven different food and medicinal plants were tested in a screening platform for identification of extracts with potential bioactivity related to insulin-dependent glucose uptake and fat accumulation. The screening platform included a series of in vitro bioassays, peroxisome proliferator-activated receptor (PPAR) γ-mediated transactivation, adipocyte di...

Background & Aim: Secondary metabolites with bioactive and functional properties in essence of aromatic plants can be useful for improvement of quality and persistence of food as natural preservative.  The aim of this study was to evaluate the in vitro antibacterial of essential oils of some of the medicinal plants collected from Chaharmahal va Bakhtiari Province, Iran. Experimental: ...

objective: regarding the anticonvulsant effects of satureja hortensis (s. hortensis) in avicenna’s book: canon of medicine; the present study was undertaken to evaluate the anti- eplileptic effects of s. hortensis aqueous and ethanolic aerial part extracts. furthermore, the mechanisms of their anticonvulsant activities were also evaluated. materials and methods: seizure was induced by pentylent...

OBJECTIVE Pancreatic islets have fewer antioxidant enzymes than other tissues and thus are vulnerable to oxidative stress. In the present study, the effects of nine specifically selected Iranian medical plants on the mitochondria function and survival of isolated rat islets were examined. MATERIALS AND METHODS In this experimental study, following laparotomy, pancreases of rats were removed a...