Ubiquitin (Ub)-binding domains (UBDs) located in Ub receptors decode the ubiquitination signal by non-covalently engaging the Ub modification on their binding partners and transduce the Ub signalling through Ub-based molecular interactions. In this way, inducible protein ubiquitination regulates diverse biological processes. The estrogen receptor alpha (ERa) is a ligand-activated transcription ...

there are some evidences on elamite seals that show iranian people had enough knowledge to construct small dome on cylindrical spaces like silo in the third millennium bc. but the foundations of large dome over square spaces were formed in the parthian period. bazeh-hur dome chamber with the corners of wood in khorasan province is the most ancient dome from the sasanian dynasty. since the sasan...

The aims of the paper are (i) to describe the annual distribution of extreme runoff events on the Mura, Drava and Sava Rivers, (ii) to demonstrate their association with moisture fluxes, and (iii) to explain their annual distribution by moisture flux climatology. Extreme runoff events were defined as rapid increases in daily mean discharge. Moisture flux anomalies were studied within six pixels...