BACKGROUND Umbilical pilonidal sinus (UPS) is a rare disease of young, hirsute, dark men with deep navels and poor personal hygiene. UPS could easily be misdiagnosed and mistreated due to its rarity and lack of awareness of the condition by physicians. However, the diagnosis is easy to establish with physical examination and a detailed history. Although it is being diagnosed and reported more f...

Riccardin D, a macrocyclic bisbibenzyl isolated from Chinese liverwort Dumortiera hirsute, has been proved to have inhibitory effect on biofilms formation of Candida albicans in in vitro study. Our present study aims to investigate the in vivo effect and mechanisms of riccardin D against C. albicans biofilms when used alone or in combination with clinical using antifungal agent fluconazole. XTT...

Adrenocortical carcinoma tissue removed from a mildly hirsute 16-year-old girl was cultured in order to assess steroidogenesis and responsiveness of the cells to adrenocorticotropic hormone (ACTH), human chorionic gonadotropin (HCG), and insulin. The cells in culture produced large amounts of androstenedione and testosterone; however, production of cortisol, which was initially high, decreased ...

The two-spotted leafhopper, Sophonia rufofascia (Kuoh and Kuoh), is an exotic pest from South-East Asia that attacks a wide variety of plant species in Hawaii. Myrica faya Aiton is an aggressive exotic weed that displaces and excludes native plants in Hawaiian forests. It has been argued that because of the high nutritional quality of its foliage, M. faya might facilitate leafhopper invasion of...

BACKGROUND The large caliber of head hair in hair transplantation imparts a coarse hairline, whereas natural hairlines are typically softer. In hirsute individuals, transplantation of leg hair to the hairline may result in a superior aesthetic appearance. OBSERVATION A total of 1025 leg hair follicles in 1 patient were grafted to an area 0.5 to 1.0 cm in front of and 0.5 to 1.0 cm internal to...

CONTEXT We undertook this study to estimate the prevalence of the various androgen excess disorders using the new criteria suggested for the diagnosis of polycystic ovary syndrome (PCOS). SETTING The study was performed at two endocrine departments at the University of Palermo (Palermo, Italy). PATIENTS The records of all patients referred between 1980 and 2004 for evaluation of clinical hy...

The relationship between hidradenitis suppurativa (HS) and hyperandrogenism is largely based on the finding of an increased free androgen index due to a low sex hormone binding globulin (SHBG). As SHBG is now believed to be regulated by factors that influence body weight, and previous studies were not controlled for body weight, we have re-evaluated the androgen status of female patients with H...

The principal urinary 17-ketosteroids (17KS) were analyzed in 16 cases of hirsutism; their conjugated forms were separately cleaved, and the liberated 17KS were chromatographed and quantitated. Six were clinically classified as cases of Stein-Leventhal syndrome and the remaining 10 as "idiopathic hirsutism." 1 The following conditions were excluded a priori: adrenal and ovarian tumors, Cushing'...

1. The percentage binding of testosterone (T) and oestradiol (E2) to sex hormone binding globulin (SHBG) and human serum albumin (HSA) was determined over a range of SHBG concentrations of 16-250 nmol of dihydrotestosterone (DHT) bound/l. It was found that the binding of both T and E2 to HSA was a function of their binding to SHBG and bore an inverse relationship to it. After removal of both SH...

To the Editor:-As a bearded anesthetist, 1 was interested to read the solution of Drs. Johnson, Bradway, and Blood to the problem of good mask ventilation in the presence of an hirsute face.' Although they are correct in their assertion that it is a frequently encountered situation, they are incorrect in their statement that the only previously published solution has been to skive the patient p...