SF3b is a U2 snRNP-associated protein complex essential for spliceosome assembly. Although evidence that SF3b contains the spliceosomal proteins SAPs 49, 130, 145, and 155 has accumulated, a protein-mediated association between all of these proteins has yet to be directly demonstrated. Here we report the isolation of a cDNA encoding SAP 130, which completes the cloning of the putative SF3b comp...

Methods “Papageorgiou” General Hospital is one of the four major hospitals of Thessaloniki, the second largest Greek city of 1.2 million inhabitants. Data was extracted from hospital databases (ICD-10 diagnoses V01-V89 for MT and X60-X84 for SA) from the year 2008 to 2014. Several variables concerning patient demographics, APACHE and SAPS II scores, length of ICU stay (LOS) and outcome were rec...

Fractures of pelvis and acetabulum are at high risk death worldwide. However, the capability mortality prediction by conventional system Simple Acute Physiologic Score (SAPS) II remains limited. Here, we hypothesized that use machine learning (ML) algorithms could provide better performance than SAPS for traumatic patients in intensive care unit (ICU). Customized ML models were built including ...

A statistical study has been performed by using two years of DMSP (Defense Meteorological Satellite Program) plasma observations to investigate the seasonal effect of SAPS (subauroral polarization stream) on the ion upflow in the duskside ionosphere of the Northern Hemisphere. There are obvious upflows occurring in the topside ionosphere around the SAPS region, exceeding 200 m s−1 at winter sol...

OBJECTIVE To determine the prevalence of infections in Brazilian intensive care units and the associated mortality by analyzing the data obtained in the Extended Prevalence of Infection in Intensive Care (EPIC II) study. METHODS EPIC II was a multicenter, international, cross-sectional prospective study of infection prevalence. It described the demographic, physiological, bacteriological, and...

Xylella fastidiosa is a xylem-limited bacterium in plant hosts and causes Pierce's disease (PD) of grapevines, which differ in susceptibility according to the Vitis species (spp.). In this work we compared X. fastidiosa biofilm formation and population dynamics when cultured in xylem saps from PD-susceptible and -resistant Vitis spp. under different conditions. Behaviors in a closed-culture sys...

Mitochondria activation factor (MAF) is a high-molecular-weight polyphenol purified from black tea that activates mitochondrial respiration. It increased the mitochondrial membrane potential and motility of sea urchin sperm, by up to 8%, to the same extent as sperm-activating peptides (SAPs) secreted by the egg. Unlike SAPs, MAF had no effect on sperm swimming behavior, suggesting that the mech...

Using ground-based magnetic field measurements and numerical simulations from the Thermosphere-Ionosphere Electrodynamic General Circulation Model (TIEGCM), a first paper (Zhang, Yamazaki, et al., 2021, doi: https://doi.org/10.1029/2021JA029681; under review) introduced potential roles of disturbance dynamo electric due to subauroral polarization streams (SAPS) on equatorial electrojet (EEJ) du...

BACKGROUND There are several scoring systems used in the prediction of outcome in critically ill patients. This study was undertaken to evaluate APACHE II, SAPS I, Sepsis score, MOF, TISS-28 and MPI scoring systems in prediction of the outcome in patients with perforative peritonitis. PATIENTS AND METHODS The prospective study of 145 patients of both sexes with perforative peritonitis was per...

INTRODUCTION Simplified Acute Physiology Score 3 (SAPS 3) was the first critical care prognostic model developed from worldwide data. We aimed to systematically review studies that assessed the prognostic performance of SAPS 3 general and customized models for predicting hospital mortality in adult patients admitted to the ICU. METHODS Medline, Lilacs, Scielo and Google Scholar were searched ...