A new method for preparing naphthyl amines from 1,5 unsaturated dicarbonyl precursors is described; the utility of this new method was proven in the syntheses of several natural products, all containing the benzo[c]phenanthridine core and enabled by a radical promoted cyclisation of the naphthyl amine products formed in the key cyclisation.

Objectives: Mono or infectious mononucleosis (IM) is often referred to as the kissing illness. Epstein-Barr virus (EBV), which causes mono, spread by saliva. Kissing, sharing a drink, eating utensils with person who has can transmit disease healthy individuals. This study investigates several bioactive compounds derived from plants forecast how effective plant-based ligands will be at preventin...

The epidermal growth factor receptor (EGFR) belongs to the HER/erbB tyrosine kinase (RTK) family, serving as a crucial target for cancer treatment. Anti-EGFR drugs, used primary treatment patients with advanced EGFR gene mutations such T790M, C797S, and L858R, have shown greater efficacy safety compared standard chemotherapy. This study aimed screen alkaloid compounds anticancer activity, extra...