The minimum clinically important difference (MCID) between treatments is recognized as a key concept in the design and interpretation of results from a clinical trial. Yet even assuming such a difference can be derived, it is not necessarily clear how it should be used. In this paper, we consider three possible roles for the MCID. They are: (1) using the MCID to determine the required sample si...

Before-and-after safety studies are becoming more desirable in lieu of traditional cross-sectional studies in establishing crash modification factors, especially after the introduction of the first version of the Highway Safety Manual (2010). We present a simple method for estimating necessary sample sizes to obtain a target precision or power when the effect is represented as a proportional ch...

In comparing or assessing methods of treatment it is vital that the appropriate number of patients is selected in order to ensure that the conclusions drawn are statistically viable. This annotation describes the relevance of a statistical power analysis in the context of hypothesis testing to the determination of the optimal sample size of a study. The power of the test indicates how likely it...

The paper reviews both the influencing factors and calculation strategies of sample size determination for survey research. It indicate the factors that affect the sample size determination procedure and explains how. It also provides calculation methods (including formulas) that can be applied directly and easily to estimate the sample size needed in most popular situations.

This procedure computes power and sample size for non-inferiority tests in two-sample designs in which the outcome is a continuous normal random variable. Measurements are made on individuals that have been randomly assigned to one of two groups. This is sometimes referred to as a parallel-groups design. This design is used in situations such as the comparison of the income level of two regions...

The paper proposes a generic color-texture feature integration framework. We propose two variants of edge based texture capturing method using filter banks of tensor products obtained from Orthogonal Polynomials (OP) OP3 of order 3 and OP5 of higher order 5 which are applied on Hybrid Color Space (HCS) for color texture feature integration. A region based unsupervised segmentation algorithm is ...

We study the sample complexity of nondeterministically testable graph parameters and improve existing bounds on it by several orders of magnitude. The technique used would be also of independent interest. We also discuss the special case of weak nondeterministic testing for uniform hypergraphs of arbitrary order.

Monte Carlo simulations are increasingly used to predict pharmacokinetic variability of antimicrobials in a population. We investigated the sample size necessary to provide robust pharmacokinetic predictions. To obtain reasonably robust predictions, a nonparametric model derived from a sample population size of >/=50 appears to be necessary as the input information.

Inspired by Diakonikolas and Kane (2016), we reduce the class of problems consisting of testing whether an unknown distribution over [n] equals a fixed distribution to this very problem when the fixed distribution is uniform over [n]. Our reduction preserves the parameters of the problem, which are n and the proximity parameter ǫ > 0, up to a constant factor. While this reduction yields no new ...