Proximal tibia resection with endoprosthetic reconstruction is a complex limb sparing procedure for tumors of the proximal tibia. Recent advances in implants and surgical techniques have made this option preferable to amputation for many patients. Long-term survival and recurrence rates are similar between limb salvage and limb ablation in the proximal tibia. Appropriate indications for limb sa...

Donor lymphocyte infusion (DLI) has the potential to significantly deepen response after allogeneic stem cell transplantation (ASCT) in multiple myeloma (MM). Subsequently, DLI offers opportunity for long-term progression-free and, most importantly, overall survival patients with MM. application is a complex procedure, whereby many factors need be considered (e.g., patient-oriented prior applic...

Forty-four patients with refractory Hodgkin's disease were treated with high-dose combination chemotherapy followed by autologous bone marrow rescue. Twenty-two patients (50%) entered complete remission within 6 months of the procedure and four other patients are free of disease progression. Only two patients have subsequently relapsed from complete remission (CR). Bone marrow suppression was t...

A 35-year-old woman underwent laparoscopic radical hysterectomy, pelvic lymphadenectomy and ovarian transposition for stage IB2 cervical adenocarcinoma. She received adjuvant concurrent chemoradiation for poor pathologic risk factors but had tumor recurrence 20 months after the surgery. Transposed ovaries were uninvolved in the recurrence and progression. Salvage chemotherapy and radiotherapy w...

introduction: management of early relapsed or refractory lymphoma [hodgkin & non- hodgkin lymphoma (hl & nhl)] is a matter of problem, especially when hematopietic stem cell support is not available. the aim of this study was to evaluate effectiveness of iev regimen ( ifosfamide, epirubicin, vp16), in lymphoma patients who are not candidate for stem cell transplantation. because the majority of...

Patients with complex periprosthetic fracture patterns of the femur may ultimately require amputation. Some authors have described the use of mega-endoprostheses as a salvage procedure. This study reports functional outcome, complications, and implant and patient survival after total femoral replacement (TFR) for salvage of periprosthetic fracture of the femur. A prospective database of 20 cons...

Prefabricated composite free flaps for complex airway reconstruction have been described for an adult series at our institution. We extended this approach to a pediatric patient with lifelong subglottic stenosis who had failed previous open airway reconstructions. A staged procedure was utilized in which a composite graft was created using conchal cartilages and a radial forearm free flap. This...

Traumatic ear amputations are relatively rare. Whenever possible, ear re-implantation should be attempted; however the choice of the surgical procedure must be judicious. In the current report, a case of complete non-microsurgical salvage of a partially amputated ear treated by the pocket technique described by Mladick was presented. The surgical technique is described in detail by serial photo...

Summary: Background: This study aimed to evaluate the differences between outcomes of patients with intermittent claudication (IC) and chronic limb threatening ischemia (CLTI) who underwent a hybrid procedure comprising common femoral artery endarterectomy endovascular therapy. Patients methods: was retrospective single-center all peripheral arterial occlusive disease (PAD) March 2007 August 20...

Patients frequently present with deformity of forearm with bone loss in either of the forearm bones due to various reasons. In this study two children suffering from chronic osteomyelitis and one having neglected Monteggia fracture were selected. In all three cases, single bone forearm reconstruction by radioulnar fusion was attempted successfully. Cosmetic and functional outcomes were evaluate...