The cancer stem cell (CSC) potency of a series structurally analogous Group 10-azadiphosphine metal complexes is reported. comprise 10 (Ni for 1, Pd 2, or Pt 3), an azadiphosphine ligand, and two chloride ligands. exhibit micromolar towards bulk breast cells CSCs cultured in monolayer systems. cytotoxicity the comparable to better than clinically used metallopharmaceuticals, cisplatin carboplat...

The effect of administering low (15 mg/L) levels of silver nanoparticles in the drinking water of broilers (n = 40) was investigated as a potential replacement for antibiotic coccidiostats (Salinomycin® or Baycox) in two trials. Four treatments were used: (1) challenged (with 3.3 x 10 Eimeria tenella oocysts via oral gavage in the first trial and 1.6 x 10 in the second trial) and medicated with...

The study was carried out to evaluate the dietary supplementation of oregano essential oil on performance and antimicrobial activity of broilers. A total of 250 day-old male were distributed in a completely randomized design divided into five groups with five replicates, each given a basal diet with avilamycin plus salinomycin (positive control) or a basal diet without added avilamycin and sali...

We report the anti-breast cancer stem cell (CSC) properties of a series Group 10-bis(azadiphosphine) complexes 1–3 under exclusively three-dimensional culture conditions. The breast CSC mammosphere potency is dependent on 10 metal present, increasing in following order: 1 (nickel complex) <2 (palladium <3 (platinum complex). Notably, 3 reduces formation and size mammospheres to greater extent t...