N 1962, we 1 published a report on the value of the comparative Usodium/Ucreatinine ratio in the diagnosis of hypertension due to renal arterial stenosis. This ratio is defined as the proportional relation between the concentration of sodium and creatinine (U5Odiu./Ucreatinine) in the urine issuing simultaneously from each ureter. We also suggested that routine performance of dehydrated-hydrate...

BACKGROUND The safety of sputum induction (SI) is well described in stable asthma, but the safety of SI in exercise-induced bronchoconstriction (EIB) has not been established. OBJECTIVES Our goals were to examine the relationship between the severity of EIB and bronchoconstriction during SI, and to determine if SI conducted after exercise challenge increases the risk of excess bronchoconstric...

BACKGROUND Hyponatremia (HN) occurs commonly in patients with acute heart failure and confers a worse prognosis. Current HN treatment varies widely, with no consensus. This study recorded treatment practices currently used for patients hospitalized with acute heart failure and HN. METHODS AND RESULTS Data were collected prospectively from 146 US sites on patients hospitalized with acute heart...

INTRODUCTION The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is the most frequent cause of hyponatremia in a hospital setting. However, detailed protocols and algorithms for its management are lacking. Our objective was to develop 2 consensus algorithms for the therapy of hyponatremia due to SIADH in hospitalized patients. MATERIAL AND METHODS A multidisciplinary group ma...

Primary pancreatic hydatid cysts are rare and its percutaneous treatment and catheterization technique has, to the best of our knowledge, not been published in literature. A 33-year-old male patient who presented with abdominal pain was evaluated by ultrasonography (US) and computed tomography examinations. Both examinations revealed a cyst in the neck of the pancreas. After the administration ...

BACKGROUND Sputum production induced by inhalation of hypertonic saline solution has been proposed as a technique to collect secretions and inflammatory cells from the airways of subjects with bronchial asthma or with a history of smoking. The aim of this study was to determine the effect of a sputum induction procedure on spirometric results and arterial oxygen saturation (SaO(2)) in asthmatic...

We have read with great interest the article by Castagnaro et al (October 1999),1 reporting a significant drop in oxygen saturation in the absence of an equivalent drop in FEV1 during sputum induction. This, however, has not been our experience. Although we agree that FEV1 may fall in asthmatics, COPD patients,2 and normal volunteers,3 we have not seen significant changes in oxygen saturation. ...

OBJECTIVE To verify the functionality through muscle grip strength in animals with obesity induced by monosodium glutamate (MSG) and in control animals, which suffered compression of the right median nerve, and treated with swimming with overload. METHODS During the first five days of life, neonatal Wistar rats received subcutaneous injections of MSG. The control group received a hypertonic s...

Previous attempts to use urinary protein profiles for diagnostic purposes have been rather disappointing with respect to their clinical validity, in part because of the insufficient reproducibility, sensitivity, and rapidity of available techniques. Therefore, a newly developed, high-throughput technique, namely surface-enhanced laser desorption/ionization (SELDI) ProteinChip array-time of flig...

OBJECTIVE To compare the diagnostic yield of AFB positivity with sputum induction to spontaneous sputum examination in suspected cases of pulmonary tuberculosis. STUDY DESIGN Comparative study. PLACE AND DURATION OF STUDY Military Hospital, Rawalpindi, from January to December 2006. METHODOLOGY Sputum specimens were collected by both techniques from 164 patients with clinical and radiolog...