Microbial superantigens (SAGs) have been implicated in the pathogenesis of human autoimmune diseases. Preferential expansion of the Vveta7 T cell receptor positive T cell subset in patients suffering from acute-onset type I diabetes has indicated the presence of a surface membrane-bound SAG. Here, we have isolated a novel mouse mammary tumor virus-related human endogenous retrovirus. We further...

BACKGROUND A lumbar drainage catheter is frequently placed intra-operatively to decrease fluid pressure on the brain in aneurysmal subarachnoid cases. In rare cases, this catheter placement can lead to intracranial hypotension, resulting in brain stem herniation termed "brain sag" and it can lead to neurological injury and may prove to be fatal. We present our patient with brain sag secondary t...

In this paper, the impacts of installing superconducting fault current limiter (SFCL)in radial and loop power distribution system are evaluated to improve voltage sag in both cases of with and without distributed generations (DG). Among various SFCLs, the hybrid type with a superconducting element in parallel with a current limiting reactor (CLR) is selected. This is more effective than resisto...

Abstract— A new development of voltage control scheme for power quality improvement such as voltage sag, swell, harmonics, and transient conditions in three-phase power systems has been proposed. Faults occurring in power distribution systems or amenities can inject the voltage sag or swell. This fault can damage or affect the power transmission and distribution. For sensitive loads, the short ...

The Apo-1/Fas antigen (CD95) mediates programmed cell death of lymphocytes when bound by Fas ligand or anti-Apo-1/Fas antibody. In contrast, the CD40 antigen provides a potent activation and survival signal to B lymphocytes when it is engaged by its T cell ligand (CD40L, gp39) or cross-linked by anti-CD40 antibody. In this study, we use human tonsillar B cells and the Ramos Burkitt's lymphoma B...

Bacterial superantigens (SAgs) have been implicated in inflammatory disease, and SAg-treated mice have increased jejunal T cells. Here we show that T84 cells (a human epithelial cell line) display increased MCP-1 and RANTES mRNA expression and protein production in response to conditioned medium from Staphylococcus aureus enterotoxin B (SEB; a model SAg)-activated immune cells. Also, MCP-1 and ...

Idiomatic utterances contribute by virtue of their aspectual class to the temporal structure of discourse – hence it is essential that theories of aspect derivation and discourse structure should encompass them. A recent claim has been made (McGinnis 2002) that the aspectual class of idiomatic expressions can be derived compositionally, by the same process as in literal language. We examine thi...

[1] Spur and groove (SAG) formations are found on the fore reefs of many coral reefs worldwide. Although these formations are primarily present in wave-dominated environments, their effect on wave-driven hydrodynamics is not well understood. A twodimensional, depth-averaged, phase-resolving nonlinear Boussinesq model (funwaveC) was used to model hydrodynamics on a simplified SAG system. The mod...

The neonatal immune response is impaired during the first weeks after birth. To obtain a better understanding of this immaturity, we investigated the development of T cell interactions with B cells in mice. For this purpose, we analyzed the immune response to three T-dependent antigens in vivo: (i) the polyclonal antibody response induced by vaccinia virus; (ii) the production of polyclonal and...