In the continuing goal of codifying the classification of musical sounds and rules for data mining we present the following classification methodology that produces a hierarchical granulation structure. The motivation for this paper is based upon the fallibility of Hornbostel/Sachs, the generic classification scheme used in Music Information Retrieval for instruments. In eliminating the redunda...

I 1959 holdt filosofen Hannah Arendt pristalen „Gedanken zu Lessing. Von der Menschlichkeit in finsteren Zeiten.“ tidsrommet 1960–1966 poeten Nelly Sachs taler ved mottagelsen av ulike priser. sine er de opptatt forholdet mellom den enkelte og verden, hver fra sitt ståsted, men begge betoner hvor viktig det å være åpen for delta i verden. utvikler begreper beskrive verden som offentlig rom, „We...

The results presented here provide the first single-cell genetic assay for Tay-Sachs disease based on real-time PCR. Individual lymphoblasts were lysed with an optimized lysis buffer and assayed using one pair of primers that amplifies both the wild type and 1278 + TATC Tay-Sachs alleles. The resulting amplicons were detected in real time with two molecular beacons each with a different colored...

Purpose. Impaction fractures of the anterior aspect of the humeral head, the reversed Hill-Sachs lesion, are common in posterior shoulder dislocation. We present a new technique to address these lesions arthroscopic-assisted with the use of a bone substitute. Methods. We report the case of a 45-year-old male with a reversed Hill-Sachs lesion after posterior shoulder dislocation. Initially a gle...

GM2 gangliosidoses are a group of lysosomal storage disorders which include Sandhoff disease and Tay-Sachs disease. Dysregulation of glutamate receptors has been recently postulated in the pathology of Sandhoff disease. Glutamate receptor association with neuronal pentraxins 1 and 2, and the neuronal pentraxin receptor facilitates receptor potentiation and synaptic shaping. In this study, we ha...