Articular cartilage lesions are a particular challenge for regenerative medicine due to cartilage low self-ability repair in case of damage. Hence, a significant goal of musculoskeletal tissue engineering is the development of suitable structures in virtue of their matrix composition and biomechanical properties. The objective of our study was to design in vitro a supporting structure for autol...

Automated jellyfish classification and orientation determination can be used to improve the robustness of an autonomous jelly tracking system. A set of training images were segmented and augmented with orientation data, and a feature vector was generated for each image. An SVM was then trained to estimate a jelly’s orientation. In simulations on unseen test images, the approach was able to corr...

Developing myocardial cells respond to signals from the endocardial layer to form a network of trabeculae that characterize the ventricles of the vertebrate heart. Abnormal myocardial trabeculation results in specific cardiomyopathies in humans and yet trabecular development is poorly understood. We show that trabeculation requires Brg1, a chromatin remodeling protein, to repress ADAMTS1 expres...

Human Wharton's jelly mesenchymal stem cells were isolated from fetal umbilical cord. Cells were cultured in serum-free neural stem cell-conditioned medium or neural stem cell-conditioned medium supplemented with Dkk-1, a Wnt/β catenin pathway antagonist, and LeftyA, a Nodal signaling pathway antagonist to induce differentiation into retinal progenitor cells. Inverted microscopy showed that aft...

The objective herein was to evaluate the effect of processing, packaging type (with and without exposure light) storage time on quality functional attributes jelly prepared from curriola pulp. experimental design a completely randomized 2 × 5 factorial design, with two levels (transparent amber) five periods (0, 3, 6, 9 12 months). In general, processing pulp determined slight increase in pheno...

background: wharton’s jelly is an unlimited source of stem cells that can be used in cell therapy and tissue engineering without any ethical concern. it has been revealed the cell-free extract could be effective to induce cell differentiation. the objective of this study was to induce wharton’s jelly-derived mesenchymal stem cells (mscs) into hepatocyte-like cells by premeabilization of the cel...

The nutritional needs of bees are supplied by nectar carbohydrates and by protein and other nutrients in pollen but little is known of how bees achieve nutritional balance. Using newly emerged caged worker honeybees (Apis mellifera scutellata), we investigated whether bees maintain their intake target when confined to pairs of imbalanced complementary diets varying in protein to carbohydrate (P...

This study evaluated the impact of processing, packages (amber and transparent glass jars), storage time on stability bioactive compounds (total phenolic vitamin C), antioxidant activity mangaba jelly. Jelly significantly (p < 0.05) decreased activity. The time, influenced all variables studied in this work, although they were not affected by packages. A significant decrease was observed during...