alzheimer's disease (ad) is a chronic neurodegenerative disease that accounts for 60 to 80 percent of all dementia cases. the exact cause of alzheimer`s disease is still unknown, but recent studies suggest neuro-inflammation as an important part of the pathogenesis of the disease. this brings in mind using non-steroidal anti-inflammatory drugs (nsaid) as treatment or prevention of the dise...

kienbock's disease, which is an idiopathic osteonecrosis and collapse of the lunate bone, is an uncommon disease in children. this report describes a case of an 11-year-old girl, who presented with avascular necrosis of lunate bone confirmed by radiographic and magnetic resonance imaging evidence. after a short period of casting, the case was fully recovered within one year. the signal change w...

background: there is no documented demographical study on iranian parkinson's disease (pd) patients, so this study was conducted to identify demographic information about patients with pd in iran, and to explore demographical differences between pd patients in iran and other countries. methods: we reviewed medical records of 1656 patients diagnosed with pd, who referred from all parts of iran t...

background and objectives: parkinson's disease (pd) is a common neuropathologic disorder that is caused by degeneration of dopaminergic neurons of dense part of nigra. oxidative stress has been found in the pathophysiology of pd. since α-pinene has strong anti-oxidant effects, the purpose of this research was to study its effects on movement disorders and memory and lipid peroxidation in p...

background & aim:parkinson's disease (pd) is a kind of disorder in the nervous system, which is characterized with multiple movement disorders. factors such as oxidative stress are the most important causes for the degeneration of dopaminergic neurons in the substantia nigra and occurrence of parkinson's disease. thus, medications that have antioxidant functions could be an interestin...

background: cushing's disease is the most prevalent cause of endogenous adrenocorticotrophic hormone hypersecretion. the aim of this study was to document the current clinical practice pattern in the management of cushing's disease by iranian endocrinologists to determine their opinions and compare them with the current clinical practice guidelines.    methods: an eight-item questionn...

alzheimer's disease (ad), the most ordinary form of dementia and extracellular accumulation of amyloid-β (aβ) in senile plaques, is an important and a main event in the pathogenesis of ad. deposition of aβ peptide initiates a spectrum of cellular responses that are interposed by the resident neuroimmune cells of the brain, the microglia. recently, a novel inflammasome signaling  pathway ha...

background: behcet syndrome is a recurrent inflammatory disorder that frequently involves the ocular system. the purpose of this study was to determine the frequency of ocular involvement in cases of behcet's disease in babol, north of iran. methods: from april 2003 to december 2009, 100 cases of behcet's disease who were admitted at the department of ophthalmology and internal medici...

Alzheimer's disease (AD) is a chronic neurodegenerative disease that accounts for 60 to 80 percent of all dementia cases. The exact cause of Alzheimer`s disease is still unknown, but recent studies suggest neuro-inflammation as an important part of the pathogenesis of the disease. This brings in mind using non-steroidal anti-inflammatory drugs (NSAID) as treatment or prevention of the disease. ...