نتایج جستجو برای: run of homozygosity
تعداد نتایج: 21168121 فیلتر نتایج به سال:
There is limited genetic information available in most African goat populations. However, improvements genomic technologies have enabled easy and effective analysis of different parameters. This study used Single Nucleotide Polymorphism (SNP) data four genotypes from Kenya; Galla (n = 12), Alpine 28), Saanen 24) Toggenburger 30). After SNP quality control, 48808 SNPs that were for analysis. Run...
Homozygosity mapping is a common method for mapping recessive traits in consanguineous families. In most studies, applications for multipoint linkage analyses are applied to determine the genomic region linked to the disease. Unfortunately, these are neither suited for very large families nor for the inclusion of tens of thousands of SNPs. Even if less than 10,000 markers are employed, such an ...
Estimating individual genome-wide autozygosity is important both in the identification of recessive disease variants via homozygosity mapping and in the investigation of the effects of genome-wide homozygosity on traits of biomedical importance. Approaches have tended to involve either single-point estimates or rather complex multipoint methods of inferring individual autozygosity, all on the b...
Rheumatoid arthritis (RA) is a chronic inflammatory disorder with a polygenic mode of inheritance. This study examined the hypothesis that runs of homozygosity (ROHs) play a recessive-acting role in the underlying RA genetic mechanism and identified RA-associated ROHs. Ours is the first genome-wide homozygosity association study for RA and characterized the ROH patterns associated with RA in th...
unemployment-inflation trade-off is known as philips curve. this relationship was first defined for england economy by professor philips since 1958. much development has been submitted by different economic schools about this innovation. in this paper, apart from dealing with the new-keynesians philips curve, the curve mentioned is estimated for iranian economy. in addition, we are going to com...
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