OBJECTIVE We present a prospective study of a microemulsion of cyclosporin to treat idiopathic nephrotic syndrome in ten children with normal renal function who presented cyclosporin trough levels between 50 and 150 ng/ml and achieved complete remission with cyclosporin. To compare the pharmacokinetic parameters of cyclosporin in idiopathic nephrotic syndrome during remission and relapse of the...

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We consider a Takagi-Sugeno-Kang (TSK) fuzzy rule based system used to model a memory-less nonlinearity from numerical data. We develop a simple and effective technique allowing to remove irrelevant inputs, choose a number of membership functions for each input, propose well estimated starting values of membership functions and consequent parameters. All this will make the fuzzy model more conc...

In this paper, we propose an adaptive knot placement algorithm for B-Spline curve approximation to dense and noisy 2D data points. The proposed is based on a heuristic rule placement. It consists in constructing distribution function by blending geometric criteria such as discrete derivatives, angular variations curvature. has been successfully compared three well known methods approximating va...

Learning from the robust mechanism of biological nervous system is critical for creating reliable neuromorphic hardware. The homeostatic inhibition plasticity rule a to balance Hebbian and resist external environmental disturbances local damage. It plays an essential role in maintaining sparse firing patterns system. This paper imitates this provides fast inhibitory circuit with memristive syna...

my paper has two parts. first, i talk about the golden rule. after introducing the rule and its global importance, i explain why many scholars dismiss it as a vague proverb that leads to absurdities when we try to formulate it clearly. i defend the golden rule against such objections. second, i talk about the golden rule in persia and islam; i consider persian sources (muslim and non-muslim) an...

1-type and biharmonic curves by using laplace operator in lorentzian 3-space arestudied and some theorems and characterizations are given for these curves.

BACKGROUND Leiden Score, is a very useful tool for predicting future development of rheumatoid arthritis (RA), among undifferentiated arthritis (UA) patients. This score has been validated in various western studies but rarely among south east Asian patients. AIMS To validate the Leiden early arthritis prediction rule in an Indian cohort of patients for predicting rheumatoid arthritis (RA) in...

OBJECTIVES Recently, a rule was developed to predict sick leave related to shoulder pain during a period of 6 months after patients have consulted a general practitioner for a new episode of shoulder pain. The objective was to evaluate the generalizability of this prediction rule by testing it in two other populations of workers who had gone for a consultation in primary care for a new episode ...