Sixteen cases of medulloepithelioma are described. Clinical data and follow-up were available on 15. Four patients underwent iridocyclectomy initially; all later needed enucleation and one had an orbital recurrence. The remaining 12 patients underwent primary enucleation. All 15 patients with follow-up are alive with no evidence of tumour recurrence. It is suggested that enucleation be performe...

Waardenburg syndrome (WS) is a genetic disorder characterized primarily by depigmentation of the skin and hair, heterochromia of the irides, sensorineural deafness, and sometimes by dystopia canthorum, and Hirschsprung disease. WS presents a large clinical and genetic heterogeneity. Four different types have been individualized and linked to 5 different genes. We report 2 cases of WS type II an...

knowledge of lidocaine and physiology of the human iris, we can only speculate on its mechanism of action and the differences between the subsets observed in our study. Dr. Sodhi has suggested several mechanisms based on a literature review. They are interesting proposals, but to what extent those mechanisms are responsible for the differing effect of lidocaine on pigmented irides, we cannot sa...

Topiramate is a sulfa-derivative antiepileptic drug which is also used for other indications such as essential tremor. A 79-year-old male was admitted to our center due to acute bilateral painless decline of vision. One month before admission, he had experienced essential tremor and treatment with topiramate 50 mg/day and propranolol 40 mg/day. Best-corrected visual acuity was 20/800 OD and 20/...

PURPOSE To investigate the effect of prior anesthesia on the time to full cycloplegia in young Chinese subjects. METHODS The amplitude of accommodation was monitored over a 50-minute interval after the application of 1% cyclopentolate hydrochloride with a pretreatment of 0.4% benoxinate (oxybuprocaine) or 0.9% saline solution (control). Using a nonlinear mathematical model, the rate of accomm...

By Erik L. Mertens, MD, FEBOphth More than 1 year ago, I started to implant the latest Visian ICL model, the V4c (STAAR Surgical), with a 0.36-mm port located in the center of the optic. This KS-Aquaport, which is designed to restore more natural aqueous flow and eliminate the need for an iridotomy, sets the Visian ICL V4c apart from the earlier model, the V4b. Because I no longer have to perfo...

Twelve patients with Fuchs's heterochromic cyclitis (FHC) were studied with simultaneous bilateral flucrescein angiography of the iris. The flow began a little earlier in the contralateral iris in 4 cases, and simultaneously in both irides in 8 cases. The radial iris vessels were narrow in 7 eyes with FHC and in the contralateral eyes of 2 elderly patients and 1 patient with pigmentary retinal ...