Arginine decarboxylase (ADC) and ornithine decarboxylase (ODC) are two important enzymes responsible for putrescine biosynthesis. In this study, a full-length ADC cDNA (MdADC) was isolated from apple [Malus sylvestris (L.) Mill. var. domestica (Borkh.) Mansf.]. Meanwhile, a partial ODC (pMdODC) could be amplified only by a second RCR from the RT-PCR products, whereas a full-length ODC could not...

This paper reports data and scholarly opinion that support the perception of systemic flaws in the management of scientific professions and the research enterprise; explores the responsibility that professional status places on the scientific professions, and elaborates the concept of the responsible conduct of research (RCR). Data are presented on research misconduct, availability of research ...

Learning objectives • To evaluate indications for PET-CT in plasma cell dyscrasias and its added value over other imaging modalities with review of literature based evidence and reference to the RCR/RCP guidelines. • To discuss the use of PET-CT and subsequent clinical impact at our institution with pictorial illustration. • To discuss the limitations and potential pitfalls of PET-CT with picto...

mTORC1 plays critical roles in the regulation of protein synthesis, growth, and proliferation in response to nutrients, growth factors, and energy conditions. One of the substrates of mTORC1 is 4E-BP1, whose phosphorylation by mTORC1 reverses its inhibitory action on eIF4E, resulting in the promotion of protein synthesis. Raptor in mTOR complex 1 is believed to recruit 4E-BP1, facilitating phos...

Penelitian bertujuan untuk: (1) mengetahui jumlah pendapatan usahatani Buncis Kenya; (2) kelayakan (3) pengaruh sarana dan faktor produksi terhadap Kenya di kecamatan Selo kabupaten Boyolali. Metode penelitian yang digunakan adalah metode deskriptif analisis, dilaksanakan secara survey berdasarkan fakta baru saja berlangsung (ex post facto) kemudian dianalisis sesuai tujuan penelitian. dilakuka...

Objectives: The objective of this study was to evaluate preoperative opioid use along a spectrum better understand the role that has on postoperative outcomes. Methods: A consecutive series patients undergoing arthroscopic RCR from 2018 2020 were included. Preoperative within one year surgery determined using state prescription drug monitoring program (PDMP). Cumulative morphine milligram equiv...

BACKGROUND Studies analysing the effect of endurance training on heart mitochondrial function submitted to in vitro anoxia-reoxygenation (A-R) are missing. The present study aimed to investigate the effect of moderate endurance treadmill training (14 weeks) against rat heart mitochondrial dysfunction induced by in vitro A-R. METHODS Respiratory parameters (state 3, state 4, ADP/O and respirat...

This study examined the metabolism of free radicals in hepatic mitochondria of goats induced by lipopolysaccharide (LPS), and investigated the effects of melatonin (MT). Forty-eight healthy goats (10±1.2 kg) were randomly selected and divided into four groups: saline control, LPS, MT+LPS and MT. The goats within each group were3 sacrificed either 3 or 6 h after treatment and the livers removed ...

Common sense suggests that increasing research funding increases research productivity. We also know that with increased productivity, the odds of receiving funding increases. So, which comes first, productivity or funding? To answer this question we used causal inference (1,2) to analyze data that was recently released (3) on over 70,000 principal investigators who had received NIH funding bet...

In order to quantitatively analyze the influence of extreme low temperature on wind turbine blade performance, considering uncertainty its operation process, this paper proposed a quantitative modeling and analysis method based nonlinear random-coefficient regression (RCR) model for performance. Compared with traditional model, RCR can better adapt complex variable operating environment turbine...