Posterior blepharitis and dry eye are common disorders with meibomian gland dysfunction (MGD), a principal driver of their pathophysiology. Meibomian is increasingly prevalent in older populations contributory hormonal imbalances. The abnormal meibum MGD has been documented to have an excess cholesterol resultant disruption the lipid layer tear film. This leads film instability due inadequate t...

Thirty-five patients with ocular rosacea were admitted to a trial of systemic oxytetracycline, 250 mg b.d. for 6 weeks. Oxytetracycline produced a significantly higher number of remissions than the placebo, 11/35. With repeated or continuous treatment 19/35 patients achieved a sustained remission for 8 months. There were no side effects. The nonspecific signs of ocular rosacea responded well to...

Idiopathic facial aseptic granuloma (IFAG) is a rare, benign pediatric dermatological lesion that occurs in children between 8 months and 13 years of age. The pathogenesis of IFAG is still unclear but it is likely to be associated with granulomatous rosacea in childhood. Here we describe a case of IFAG in a 13-year-old boy who showed a dramatic response to oral doxycycline and topical metronida...

Rosacea is a chronic inflammatory skin condition with neurovascular components. Calcitonin gene-related peptide (CGRP) hypothesized to play key role in the pathophysiology of rosacea, but evidence remains limited. In this study, we aimed describe effect CGRP monoclonal antibodies (MAbs) on rosacea signs and symptoms. We conducted retrospective cohort study at single academic center from 2016-20...

PURPOSE To correlate tear fluorescein clearance with interleukin-1alpha (IL-1alpha) concentration and gelatinase B (matrix metalloproteinase [MMP]-9) activity in the tear fluid of patients with ocular rosacea and normal control subjects. METHODS Gelatinase activity was evaluated by gelatin zymography in tear fluid obtained from 13 patients with ocular rosacea (including 1 patient with recurre...

How to cite this article: Tatu AL. The use of a topical compound cream product with chitosan, silver sulfadiazine bentonite hidrogel and lactic acid for the treatment of a patient with rosacea and ulcerated livedoid vasculopathy. Our Dermatol Online. 2015;6(4):456-459. Submission: 01.06.2015; Acceptance: 28.07.2015 DOI: 10.7241/ourd.20154.124 Th e use of a topical compound cream product with ch...