BACKGROUND Some patients with Prader-Willi Syndrome (PWS) have symptoms of constipation, but bowel function in PWS has never been systematically evaluated. The aim of the present study was to describe colorectal function in PWS by means of validated techniques. METHODS Twenty-one patients with PWS (14 women, age 17-47 (median = 32)) were evaluated with the Rome III constipation criteria, stoo...

a CNR ISC UOS Roma Sapienza, Sapienza University of Rome, Rome, 00185, Italy b SAIMLAL Dept., Morpho-functional Sciences, Sapienza University of Rome, Rome, Italy c MIRCen, Commissariat à l'Energie Atomique, Fountain Aux Roses, France d ImpAct Team, Lyon Neuroscience Research Center, Lyon, France e SAIMLAL Dept., Morphogenesis & Tissue Engineering, Sapienza University of Rome, Rome, Italy f Neu...

AIM The purpose of this study was to describe the occurrence of self report bloating and related factors in patients with irritable bowel syndrome (IBS). BACKGROUND Bloating symptoms are common in patients with IBS and have significant impact on normal daily function. PATIENTS AND METHODS This study was a community-based cross-sectional survey that conducted using a valid questionnaire base...

BACKGROUND AND OBJECTIVES Chronic abdominal pain is one of the most frequent reasons for medical consultation. There is, however, no well-established protocol for its diagnostic approach and, most of the times, investigation becomes an expensive and invasive medical practice. This review aimed at explaining visceral pain pathophysiology and establishing diagnostic and therapeutic goals for thes...

Rome III diagnostic criteria separate patients with idiopathic chronic constipation into mutually exclusive categories of constipation-predominant irritable bowel syndrome (IBS-C) or functional constipation (FC). However, several experts think that these conditions are not different disorders, but parts of a continuum. To shed light on this issue, we examined studies that compared IBS-C with FC...

BACKGROUND The diagnostic golden standard for gout is to detect monosodium urate (MSU) crystals in synovial fluid. While some gout classification criteria include this variable, most gout diagnoses are based on clinical features. This discrepancy between clinical practice and classification criteria can hinder gout epidemiological studies. Here, the objective was to validate gout diagnoses (Int...

Respiratory Unit, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy ENT Department, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy Department of Imaging, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy Department of Pediatric Surgery, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy Department of Pathology, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy Department of Ped...

When Policy Topic is covered Biofeedback for constipation in adults may be considered medically necessary for patients with dyssynergia-type constipation as demonstrated by meeting all 3 of the following criteria: 1. Symptoms of functional constipation that meet ROME III criteria (see Policy Guidelines). 2. Objective physiologic evidence of pelvic floor dyssynergia (see Policy Guidelines) demon...

Author details Viral Hepatitis Unit, Department of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, Rome, Italy. Epidemiology Unit, Department of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, Rome, Italy. Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy. Center for Immunobiologicals Resea...

Antonio Carbone , Giovanni Palleschi , Giulio Tomiselli , Maurizio Inghilleri , Rocco Rago , Andrea Lenzi , Antonio Luigi Pastore * Neuro-Urology Unit, University of Rome ‘‘La Sapienza’’ Polo Pontino, Rome, Italy Department of Neurosciences, University of Rome ‘‘La Sapienza’’, Rome, Italy Andrology Unit, S. Maria Goretti Hospital, Latina, Italy Department of Endocrinology, University of Rome ‘‘...