In underground tunnels or caverns, time-dependent deformation or failure of rock mass, such as extending cracks, gradual rock falls, etc., are a costly irritant and a major safety concern if the time-dependent damage of surrounding rock is serious. To understand the damage evolution of rock mass in underground engineering, an in situ experimental testing was carried out in a large belowground t...

Original scientific paper Rock generally contains various micro-cracks, fissures, pores, joints, and other defects. These defects affect the mechanical properties of rock. In order to clarify the influence of native fissures on rock deformation and failure modes, a laboratory study was carried out using the fissured dolomite, and acoustic wave velocity measurement and natural water absorption t...

Asymmetric dimethylarginine (ADMA) induces vascular smooth muscle cells (VSMCs) migration. VSMC phenotype change is a prerequisite of migration. RhoA and Rho-kinase (ROCK) mediate migration of VSMCs. We hypothesize that ADMA induces VSMC migration via the activation of Rho/ROCK signal pathway and due to VSMCs phenotype change. ADMA activates Rho/ROCK signal pathway that interpreted by the eleva...

rndetermination of rock mass deformation modulus is very important in different projects, especially in civil and mining engineering works. in-situ measurements such as dilatometer, plate load and flat jack methods may be applied to determine the deformation modulus. however, these methods are very expensive and time- consuming. analytical methods are very useful approaches which can also be us...

Abstract The consolidation of earth and rock dam foundations its effect on stability is a key concern in water conservancy transportation projects. It common to use the vacuum combined pre-pressure method deal with soft ground foundation, where reasonable selection soil coefficient one important factors determine success project. In this paper, numerical simulation used study strength law found...

Evaluating rock masses for dam foundations, especially heterogeneous (flysch), becomes imperative and requires accurate geomechanical classifications. The rocks at the Kanarwe river basin, a proposed site (Goma-Qazan near Khewata, Sura Qalat villages), mainly consist of interlaying massive carbonate Aqra Formation with flysch Tanjero Formation. Therefore, selecting appropriate types is challeng...

Rock abrasiveness is ability of rock to wear down the working tool during the mutual interaction between the working indentor and the rock in the mechanical rock cutting process. The cutting indentor is worn down during the interaction, which changes its geometric dimensions causing the enlargement of a contact area between the tool and the rock surface. The changes in these dimensions conseque...

In this paper we present a stereo feature-based method using SIFT (Scale-invariant feature transform) descriptors. We use automatic feature extractors, matching algorithms between images and techniques of robust estimation to produce a DTM (Digital Terrain Model) using convergent shots of a rock glacier.The geomorphologic structure observed in this study is the Veleta rock glacier (Sierra Nevad...

Malignant astrocytomas are highly invasive neoplasms infiltrating diffusely into regions of normal brain. Whereas the molecular and cellular mechanisms governing astrocytoma invasion remain poorly understood, evidence in other cell systems has implicated a role for the Rho-GTPases in cell motility and invasion. Here, we examine how the inhibition or activation of Rho-kinase (ROCK) affects astro...