In this paper, we study theoretically and experimentally the friction between a rough parabolic or conical profile and a flat elastomer beyond the validity region of Amontons' law. The roughness is assumed to be randomly self-affine with a Hurst exponent H in the range from 0 to 1. We first consider a simple Kelvin body and then generalize the results to media with arbitrary linear rheology. Th...

Future space based deployable telescopes will be subject to non-atmospheric disturbances. Jitter and optical misalignment on a spacecraft can be caused by mechanical noise of the spacecraft, and settling after maneuvers. The introduction of optical misalignment and jitter can reduce the performance of an optical system resulting in pointing error and contributing to higher order aberrations. Ad...

We study the rms peculiar velocity of clusters as a convenient statistic to put constraints on cosmological models. This statistic is easy to compute theoretically given a model for the power spectrum; we show that with some assumptions it can be directly related to the quantity Ω 0 σ8. We develop a likelihood method for estimating the rms peculiar velocity of clusters from line-of-sight veloci...

Bulk micromachining in silicon and glass wafers and subsequent silicon-to-glass anodic bonding have been used for the realization of an electrostatic rms-to-dc converter. A suspended membrane has been designed for: large dynamic operating range (detection limit by minimum mechanical-thermal noise and high value of the pull-in voltage), maximum bandwidth (low series resistance, high second harmo...

Introduction: One of the possible techniques to cope with the restrictions imposed by llow supply voltages is instantaneous companding [l], which is an inherent characteristic of translinear (TL) filters [2], also called exponential state-space filters [3]. TL filters exploit the exponential large-signal behaviour of the bipolar, or weak inversion MOS, transistor both for an expanding capacitan...

This project involves the design of a CMOS RF RMS Detector that converts the RMS voltage amplitude of an RF signal to a DC voltage. Its high input impedance and small area make it suitable for the built-in-testing of critical RF blocks of a transceiver such as a Low Noise Amplifier (LNA) and Power amplifier (PA) without affecting their performance and with minimum area overhead. DESCRIPTION: Th...

A vertically integrated monopoly is compared to a decentralised market arrangement where production is segmented between a Labour Managed Firm producing an input used by a pro...t maximiser manufacturer of a ...nal good. Surprisingly, in some circumstances the decentralised vertical arrangement is superior to the integrated one. JEL Classi...cation: L12, L13, L 32, P13

Purpose: Rhabdomyosarcoma (RMS) is a common pediatric soft-tissue tumor. In this study, we evaluated the efficacy and selectivity of drozitumab, a death receptor DR5-targeted therapeutic antibody, in RMS preclinical models. Experimental Design: A panel of 11 RMS cell lines was used for in vitro studies. The molecular marker predictive of response to drozitumab was interrogated. Selected RMS cel...

BACKGROUND Rheumatic heart disease (RHD) is a serious health concern in developing countries. Rheumatic mitral stenosis (RMS) is the most long-term sequel in RHD. The neutrophil to lymphocyte ratio (NLR) is a novel marker, and a higher NLR has been associated with poor clinical outcomes in various cardiovascular disorders. We evaluated the availability of NLR to predict severity of mitral steno...