Mitochondrial damage and dysfunction occur during ischemia and modulate cardiac function and cell survival significantly during reperfusion. We hypothesized that transplantation of autologously derived mitochondria immediately prior to reperfusion would ameliorate these effects. New Zealand White rabbits were used for regional ischemia (RI), which was achieved by temporarily snaring the left an...

OBJECTIVES Diabetes mellitus (DM) and renal impairment (RI) are both independent predictors of mortality after coronary artery bypass graft surgery (CABG). The two conditions often coexist, yet the impact on long-term prognosis after CABG of each factor relative to the other and the two in combination is uncertain. METHODS We undertook a prospective cohort study of 4869 patients who underwent...

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A recombinant form of the high aYnity, natural inhibitor of tumour necrosis factor á (TNFá) is currently under development for the treatment of rheumatoid arthritis (RA). This molecule is referred to as recombinant-methionyl soluble TNF-type I receptor (r-metHu-sTNF-RI or sTNF-RI). Recombinant sTNF-RI is an Eschericia coli derived recombinant, truncated, monomeric form of the 4-domain soluble T...

Application of Random Indexing (RI) to extractive text summarization has already been proposed in literature. RI is an approximating technique to deal with high-dimensionality problem of Word Space Models (WSMs). However, the distinguishing feature of RI from other WSMs (e.g. Latent Semantic Analysis (LSA)) is the near-orthogonality of the word vectors (index vectors). The near-orthogonality pr...

The ribonuclease inhibitor (RI) is a cytosolic protein and a potent inhibitor of bovine pancreatic ribonuclease (RNase A). Amphibian homologues and variants of RNase A that evade RI are cytotoxic. Here, we employ RNA interference along with amphibian and mammalian ribonucleases to demonstrate that RI protects cells against exogenous ribonucleases. These data indicate an imperative for the molec...

Formation of the enzyme alkaline phosphatase in E. coli is under the genetic control of three genes. One of these, the P gene, specifies the structure of the enzyme molecule.1-' The other two genes, Ri and R2, regulate the rate of formation of the enzyme. In the wild-type strain (P+ Ri + R2+), the rate can vary over a thousandfold range, depending on the concentration of orthophosphate in the g...

INTRODUCTION Optical techniques are routinely used to size and count extracellular vesicles (EV). For comparison of data from different methods and laboratories, suitable calibrators are essential. A suitable calibrator must have a refractive index (RI) as close to that of EV as possible but the RI of EV is currently unknown. To measure EV, RI requires accurate knowledge of size and light scatt...

In this paper we survey recent works on rational inattention (RI) in macroeconomics within the dynamic linear-quadratic-Gaussian (LQG) setting. We first discuss how RI affects consumption smoothness and sensitivity, precautionary savings, asset pricing, portfolio choice, and aggregate fluctuations in the univariate case. We then discuss the applications of RI to macroeconomic models of permanen...