OBJECTIVE Intraoperative localisation of the sensorimotor cortex using the phase reversal of somatosensory evoked potentials (SEPs) is an essential tool for surgery in and around the perirolandic gyri, but unsuccessful and perplexing results have been reported. This study examines the effect of tumour masses on the waveform characteristics and feasibility of SEP compared with functional neurona...

macroH2A is an H2A variant with a highly unusual structural organization. It has a C-terminal domain connected to the N-terminal histone domain by a linker. Crystallographic and biochemical studies show that changes in the L1 loop in the histone fold region of macroH2A impact the structure and potentially the function of nucleosomes. The 1.6-A X-ray structure of the nonhistone region reveals an...

The following propositions are true: (1) Let X be a set, p be a permutation of X, and x, y be elements of X. Then p +· (x, p(y)) +· (y, p(x)) is a permutation of X. (2) Let f be a function and x, y be sets. Suppose x ∈ dom f and y ∈ dom f. Then there exists a permutation p of dom f such that f +· (x, f(y)) +· (y, f(x)) = f · p. Let X be a finite non empty subset of R. The functor minX yielding ...

Three target-specific oral anticoagulants (TSOACs)-dabigatran, rivaroxaban, and apixaban-have been approved by the FDA to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation; however, no agents are currently approved to reverse the anticoagulant effects of these TSOACs in cases of active bleeding. This review discusses the benefits and risks of these...

The effect of theta pulse stimulation (TPS) on pentylenetetrazol (PTZ)-induced long-term potentiation of population spikes (PS) was studied in the hippocampal CA1 in vitro. A transient PTZ application produced a long-lasting enhancement of PS amplitude. A 3-min episode of TPS delivered at a higher intensity produced complete reversal of the PTZ potentiation when delivered during the last minute...

We report new paleomagnetic data for the Middle Pleistocene hominid-bearing strata in the Sima de los Huesos, North Spain. Sediments (brown muds with human and bear fossils and the underlying sterile clayey and sandy unit) preserve both normal and reversed magnetic components. The sterile unit has exclusively reversed magnetization, dating back to the Matuyama Chron, and thus is Lower Pleistoce...

Objectives: The objective of this study was “to Find out the utility of loopogram / contrast study routinely done before the ileostomy stoma reversal in patients of typhoid perforation necessitating stoma formation”. Study Design; It was an observational descriptive study. Place and Duration of Study: This study was conducted at the Surgical Department and Radiology Departments, Sheikh Zayed Me...

Fmr1 knockout mice are an animal model for fragile X syndrome, the most common form of heritable mental retardation in humans. Fmr1 knockout mice exhibit macro-orchidism and cognitive and behavioural deficits reminiscent of the human phenotype. In the present study additional behavioural and cognitive testing was performed. Knockouts and control littermates were subjected to a spatial learning ...

MzScheme’s continuation marks provide a flexible mechanism for implementing a number of useful language features and tools. We demonstrate the simplicity and utility of continuation marks by adapting them for JavaScript as frame-based stack marks using the Rhino implementation, showing a simple model of their behavior, and using them to build a toy debugger. Along the way, we discover a few int...

Switchable polarization makes ferroelectrics a critical component in memories, actuators and electro-optic devices, and potential candidates for nanoelectronics. Although many studies of ferroelectric switching have been undertaken, much remains to be understood about switching in complex domain structures and in devices. In this work, a combination of thin-film epitaxy, macro- and nanoscale pr...