Previous studies on negative selection of T cells to sheep erythrocytes in irradiated mice showed that CBA (I-Ak,I-Ek) (kk) T cells comprise two subgroups of cells restricted by I-A (A alpha-A beta) and I-A/E (E alpha-E beta) molecules. Selection of the I-A/E-restricted by I-A (A alpha-A beta) and I-A/E (E alpha-E beta) molecules. Selection of the I-A/E-restricted subset requires that the donor...

Hepatitis C virus (HCV) variation in specific T-cell epitopes may represent a mechanism of viral persistence in chronic infection. We examined the HCV non-structural protein 3 (NS3), including the immunologically relevant epitopes HCV NS3-2 KLVALGINAV (human leukocyte antigen [HLA]-A2-restricted) and HCV NS3-1391 LIFCHSKKK (HLA-A3-restricted), in 22 HLA-A2+ patients with chronic infection. Sign...

Recently, a lot of attention is given to income variations occurring at the top of the income distribution. “What happens to the top 1%?” is a question of crucial importance on the political level (Occupy Wall Street Movement) as well as on income inequality measurement level. Despite this increased interest, there is no rigorous measurement framework available in the literature for the measure...

The patterns of access to primary health care for 27 154 people were examined, using the raw data of the 1974 General Household Survey about self-reported morbidity and use of services. Access rates were calculated for four categories of health: the not ill, the acutely sick, the chronically sick without restricted activity, and the chronically sick with restricted activity. Contrary to the con...

Nanoscale heterostructures are generally characterized by local strain variations. Because the atoms in such systems can be irregularly positioned, theroretical models and parameterizations that are restricted to hydrostatic and uniaxial strain are generally not applicable. To address this shortcoming, a method that enables the incorporation of general distortions into the empirical tight bindi...

In this article we present a methodology by which an autonomous system (AS) can estimate the stability of their BGP routes without requiring access to restricted BGP data. We demonstrate a novel measurement approach using DNS anycast as an indicator of routing instability. Using this method, even end-users may monitor their ISP’s routing stability, something which was previously infeasible with...

Recently, considerable effort has been spent on showing that Lexicographic Breadth First Search (LBFS) can be used to determine a tight bound on the diameter of graphs from various restricted classes. In this paper, we show that, in some cases, the full power of LBFS is not required and that other variations of Breadth First Search (BFS) suffice. The restricted graph classes that are amenable t...