Nineteen asthmatic volunteers underwent methacholine-induced asthma to the point when tightness in the chest was just sensed (threshold symptom). Changes in the following indices of lung function were measured--static lung volumes, forced expiratory volume in one second, and airways conductance. The increase in airways resistance necessary for threshold detection was at least double that previo...

Background & Aims of the Study: Respiratory diseases are considered as the most important occupational diseases and the absence in the workplaces. Workers in the tile and ceramic industries are exposed to high concentrations of dusts. The main aim of the present study was to evaluate the pulmonary reactions and pulmonary function tests associated with exposure to dust among workers ...

BACKGROUND Bronchiolitis is the most common cause of lower respiratory tract illness in infancy, and hospital admission rates appear to be increasing in Canada and the United States. Inhaled beta agonists offer only modest short-term improvement. Trials of racemic epinephrine have shown conflicting results. We sought to determine if administration of racemic epinephrine during hospital stay for...

Patients 259 consecutive adults >16 years of age presenting with acute bronchitis, defined as a new acute lower respiratory tract illness (ie, illness for <21 d; main symptom of cough; >1 symptom of sputum production, dyspnoea, wheeze, or chest discomfort or pain; and no alternative explanation), who were not under medical supervision for an underlying disease such as asthma, chronic obstructiv...

Epidemiological questionnaires have failed to identify individuals with severe asthma. The extent of symptoms of asthma can, however, be easily established in epidemiology, by identification of multiple symptoms. We hypothesise that reporting of multiple symptoms of asthma reflects uncontrolled disease and is a sign of more severe asthma. The aims of the current study were, therefore, to determ...

background: hyperprolactinemia is the most common endocrine disorder in hypothalamic-pituitary axis and has been reported in variable levels in patients with overt primary hypothyroidism. we decided to determine the prevalence of hyperprolactinemia and clinical related symptoms in subclinical hypothyroidism patients. methods: in this cross sectional study, prolactin levels of 481 subclinical hy...