AIMS To compare the efficacy, safety and tolerability of linagliptin or placebo administered for 24 weeks in combination with pioglitazone in patients with type 2 diabetes mellitus (T2DM) exhibiting insufficient glycaemic control (HbA1c 7.5-11.0%). METHODS Patients were randomized to receive the initial combination of 30 mg pioglitazone plus 5 mg linagliptin (n = 259) or pioglitazone plus pla...

permethrin and cypermethrin are synthetic pyrethroids, belonging to a group of insecticides with low mammalian toxicity and high insecticidal activity. the present study evaluated sub-acute toxicity of dermally administrated permethrin and cypermethrin in mice. behavioral examination included assessments of lethality, weight gain, grooming, analgesymetry, anxiety, grasping, motor activity, and ...

V enous thrombosis is a fairly common disorder that manifests mainly as deep vein thrombosis of the leg or pulmonary embolism. It affects 1 in 1000 individuals annually and has a substantial mortality rate. 1 Its causes are both genetic (prothrombotic abnormalities sometimes referred to as a group as thrombophilia) and acquired. 2 Among the latter are cancer, female hormone use, and all forms o...

the mobility and bioavailability of trace elements in the agricultural soils are extremely important in assessing the risk of toxicity to the growing plants. a five step sequential extraction procedure (sep) has been employed to study the speciation of as, sb, cr, cu, cd, pb, zn, ni, fe and mn in 18 soil samples neighboring an industrial complex in isfahan, central iran. enrichment factor (ef) ...

Permethrin and Cypermethrin are synthetic pyrethroids, belonging to a group of insecticides with low mammalian toxicity and high insecticidal activity. The present study evaluated sub-acute toxicity of dermally administrated permethrin and cypermethrin in mice. Behavioral examination included assessments of lethality, weight gain, grooming, analgesymetry, anxiety, grasping, motor activity, and ...

An n-dimensional chair consists of an n-dimensional box from which a smaller n-dimensional box is removed. A tiling of an n-dimensional chair has two nice applications in some memories using asymmetric codes. The first one is in the design of codes which correct asymmetric errors with limited-magnitude. The second one is in the design of n cells q-ary write-once memory codes. We show an equival...

We propose a tamper-evident storage system based on probe storage with a patterned magnetic medium. This medium supports normal read/write operations by outof-plane magnetisation of individual magnetic dots. We report on measurements showing that in principle the medium also supports a separate class of write-once operation that destroys the out-of-plane magnetisation property of the dots irrev...

Furthermore, the cost and cost effectiveness of using both cadavers and artificial tissues can be quite high and quite low respectively. Once, for example, a hand has been dissected and sutured, the tissue will be in a state that no longer provides a useful subject to practise on. It must then be destroyed and a replacement bought. One limb may provide several opportunities to practise suturing...

a study was carried out to examine the effect of different levels of herbal methionine and dl-methionine on the growth performance and immunocompetence of broiler chickens fed on a corn-soybean meal diet. a total of 225 old male broiler chickens (ross 308) were used as experimental samples in a completely randomized design. they were randomly assigned to 9 treatments each of 5 replicates in eve...