BACKGROUND Endostatin is a C-terminal fragment of collagen XVIII which is a component of basement membranes with the structural properties of both collagens and proteoglycans. Endostatin has a major role in angiogenesis which is intimately associated with bone development and remodeling. Signaling between the endothelial cells and the bone cells, for example, may have a role in recruitment of o...

The long-term course to lumbar intervertebral disc herniation (LDH) patients receiving integrative Korean medicine treatment and predictive factors associated with disc resorption were investigated. LDH patients who received integrative Korean medicine treatment from February 2012 to December 2015 and were registered in the "longitudinal project for LDH on MRI" were included. Disc resorption am...

External apical root resorption is an iatrogenic consequence of orthodontic treatment, although it may also occur in the absence of orthodontic treatment. Root resorption causes root shortening and breaks the integrity of teeth arch and this is very important for successful orthodontic treatment. Orthodontics is probably the only dental specialty that actually uses the inflammatory process as a...

OBJECTIVE The aim of this study was to evaluate predisposing factors among patients who developed moderate or severe external root resorption (Malmgren's grades 3 and 4), on the maxillary incisors, during fixed orthodontic treatment in the permanent dentition. METHODS Ninety-nine patients who underwent orthodontic treatment with fixed edgewise appliances were selected. Patients were divided i...

PURPOSE This study was performed to evaluate the incidence and degree of external apical root resorption of maxillary incisors after orthodontic treatment and to evaluate particular associated factors related to external apical root resorption. MATERIALS AND METHODS The records and maxillary incisor periapical radiographs of 181 patients were investigated. Crown and root lengths were measured...

Nobiletin, a polymethoxy flavonoid (PMF), inhibits systemic bone resorption and maintains bone mass in estrogen-deficient ovariectomized mice. This study examined the anti-inflammatory effects of PMFs, nobiletin, and tangeretin on lipopolysaccharide (LPS)-induced bone resorption. Nobiletin and tangeretin suppressed LPS-induced osteoclast formation and bone resorption and suppressed the receptor...

UNLABELLED Idiopathic cervical resorption is a rare form of external resorption, usually with no external signs, and can be misdiagnosed as dental caries or other types of tooth resorption. Here we report a case in which, during routine radiography, an asymptomatic lower right molar presented with a radiolucency at the cervical region, with no obvious aetiologic factor identified. CLINICAL RE...