This study investigated interobserver (two observers) and intrasubject (two measurements) reproducibility of QT dispersion from abnormal electrocardiograms in patients with previous myocardial infarction, and compared a user-interactive with an automatic measurement system. Standard 12-lead electrocardiograms, recorded at 25 mm.s-1, were randomly chosen from 70 patients following myocardial inf...

Purpose. To determine the intraexaminer repeatability and interexaminer reproducibility of tear meniscus height (TMH) and noninvasive Keratograph tear breakup time (NIKBUT) measurements obtained with the Keratograph 5M (K5M) in a sample of healthy and dry eye populations. Methods. Forty-two patients with dry eye disease (DED group) and 42 healthy subjects (healthy group) were recruited in this ...

BACKGROUND Several quantification algorithms for measuring left ventricular (LV) size and function are used in clinical and research settings. The aims of this study were to investigate the effects of measurement algorithm and beat averaging on the reproducibility of measurements of the left ventricle and to assess the magnitude of agreement among the algorithms in children with dilated cardiom...

INTRODUCTION Quantitative longitudinal magnetic resonance imaging and spectroscopy (MRI/S) is used to assess progress of brain disorders and treatment effects. Understanding the significance of MRI/S changes requires knowledge of the inherent technical and physiological consistency of these measurements. This longitudinal study examined the variance and reproducibility of commonly used quantita...

STUDY OBJECTIVES To evaluate features of the peak expiratory flow (PEF) test protocol, and to characterize patterns of reproducibility in multiple PEF measurements. DESIGN Cross-sectional study. SETTING University population. PARTICIPANTS Two hundred twenty-three healthy adults. INTERVENTIONS Participants recorded five PEF measurements in each of five sessions per day for 1 week. MEAS...

in genomics, the ability to amplify rare transcripts has enabled rapid advances in the understanding of gene expression patterns in human disease. the inability to increase the copy number and to detect the signal of rare proteins as unique species in biological samples has hindered the ability of proteomics to dissect human disease with the same complexity as genomic analyses. advances in nano...

BACKGROUND AND PURPOSE Infarct volume is increasingly used as an outcome measure in clinical trials of therapies for acute ischemic stroke. We tested which of 5 different methods to measure infarct size or volume on CT scans has the highest reproducibility. METHODS Infarct volume and total intracranial volume were measured with Leica Q500 MCP image analysis software, or with a caliper, on 38 ...

RATIONALE AND OBJECTIVES The authors assessed the reliability and reproducibility of volumetric measurements of olfactory bulbs and tracts (OBTs) and temporal lobes (TLs) with magnetic resonance (MR) imaging. METHODS Repetitive MR imaging of two phantoms and OBTs and TLs of patients was performed. Regions of interest were manually drawn around the relevant structures, and their volumes were m...