The combination of citric acid-tartaric acid and sodium bicarbonate in effervescent granules has an important role providing effect. Citric tartaric are organic acids that can react with when they come contact water. This reaction results the release carbon dioxide gas, which a splitting effect makes dissolve rapidly Research on formulation evaluation andaliman fruit ethanol extract aims to opt...

BACKGROUND AND METHODS The aim of this study was to develop an immediate-release pellet formulation with improved drug dissolution and adsorption. Carbamazepine, a poorly water-soluble drug, was adsorbed into mesoporous silica (SBA-15-CBZ) via a wetness impregnation method and then processed by extrusion/spheronization into pellets. Physicochemical characterization of the preparation was carrie...

Objective: The objective of the study was to prepare and evaluate formulation granules effervescent from kirinyuh mareme leaves as an antioxidant.
 Methods: method making with wet granulation method. used for granules, meanwhile, evaluations included organoleptic tests, water content, solubility time, pH preparation, compressibility, flow time angle repose antioxidant activity.
 Resul...

OBJECTIVE Assess the ability of facial reanimation surgery to restore affect display in patients with severe facial paralysis. STUDY DESIGN Survey of healthy observers' perception of change in facial visage from preoperative to postoperative state. SETTING Academic tertiary referral center. MAIN OUTCOME MEASURES Observer graded affect display. METHODS Ninety naive observers completed a ...

A set of suitable parameter values is crucial in discrete element method (DEM) simulations. As a non-spherical particle, the coefficients rolling friction between maize seed particles and boundary are hard to measure directly must be obtained by calibration. In this paper, taking three representative varieties as research objects, necessity for accurate calibration boundaries investigated. Subs...

The powder spreading is a vital step of powder-based additive manufacturing (AM) processes. quality spread can considerably influence the properties fabricated parts. Poorly packed beds with high surface roughness result in printed part layers large porosity and low dimensional accuracy, leading to poor mechanical properties. Therefore, spreadability its dependence on process parameters charact...

The objective of this study is to develop crystallo-co-agglomeratesof metronidazole having improved physicochemical, compressibility andsolubility properties. process agglomeration employed the use ofdichloromethane (good solvent), ethanol (bridging liquid) and distilled water (poorsolvent). Micromeritic properties co-agglomerates werestudied in terms bulk density, tapped Carr's index, Hausner’...

Aiming at the lack of accurate and reliable discrete element simulation parameters in study soilmachine interaction mechanism design machinery planting areas rhizomes hilly mountainous areas, EDEM software was used to calibrate parameters. The soil angle repose test contact between particles, sliding machinery. Box-Behnken optimization method establish multiple regression model angle, optimal p...

Objective: Evaluate the physical-chemical properties and characterize microstructure of four varieties traditional Mexican chili (Capsicum annuum L.) powders: “Arbol”, “Guajillo”, “Piquin” “Mole ranchero” (Ancho chili).
 Design/methodology/approach: Physical-chemical powders were evaluated by means moisture content, particle size, aerated tapped bulk density, Carr index, Hausner ratio, ang...