نتایج جستجو برای: reporter gene

تعداد نتایج: 1151125  

Journal: :FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999
A Pazirandeh Y Xue I Rafter J Sjövall M Jondal S Okret

Previous data have suggested that glucocorticoids (GCs) are involved in the differentiation of thymocytes into mature T cells. In this report we demonstrate that the mouse thymic epithelial cells (TEC) express the cytochrome P450 hydroxylases Cyp11A1, Cyp21, and Cyp11B1. These enzymes, in combination with 3beta-hydroxysteroid dehydrogenase (3betaHSD), convert cholesterol into corticosterone, th...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004
Martina Anton Constanze Wittermann Roland Haubner Marcus Simoes Sybille Reder Bryan Essien Bettina Wagner Julia Henke Wolf Erhardt Steffi Noll Neil R Hackett Ronald G Crystal Markus Schwaiger Bernd Gansbacher Frank M Bengel

UNLABELLED Coexpression of a reporter gene and a therapeutic gene may allow for noninvasive monitoring of cardiac gene therapy. We sought to evaluate the usefulness of an adenoviral vector expressing mutant herpesviral thymidine kinase reporter gene (HSV1-sr39tk) and vascular endothelial growth factor (VEGF) 121 in independent expression cassettes (Ad4tk). METHODS Accumulation of 14C-2'-fluor...

Journal: :Plant Journal 2021

SUMMARY Gene expression is controlled and regulated by interactions between cis ‐regulatory DNA elements (CREs) regulatory proteins. Enhancers are one of the most important classes CREs in eukaryotes. Eukaryotic genes, especially those related to development or responses environmental cues, often multiple enhancers different tissues and/or at developmental stages. Remarkably, little known about...

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