PURPOSE Vascular targeted photodynamic therapy represents the newest generation of photodynamic therapy and a new paradigm for minimally invasive ablative therapy. We report a pilot trial of vascular targeted photodynamic therapy to evaluate the effect on porcine renal tissue. MATERIALS AND METHODS Pigs underwent continuous infusion of WST-09 (Negma-Lerads, Toussous le Noble, France) and conc...

INTRODUCTION Although most urologists agree that failures after laparoscopic pyeloplasty occur usually within a year after the operation, late failures are also reported. AIM To assess late results of laparoscopic pyeloplasty. MATERIAL AND METHODS Seventy-eight of ninety-five patients who had been operated on between November 2001 and September 2009 were notified about the possibility of di...

This report is the summary of presentations at the symposium sponsored by the American Society for Pharmacology and Experimental Therapeutics, April 26-30, at Experimental Biology 2014 in San Diego, CA. The presentations focused on the role of transporters in imaging in health and disease and on assessing transporter function in vivo. Imaging is an important diagnostic tool in clinics and is a ...

This report is a summary of the presentations of a symposium sponsored by the American Society for Pharmacology and Toxicology (ASPET) held April 26-30 at Experimental Biology 2014 in San Diego, CA. The presentations focused on the role of transporters in imaging in health and disease and on assessing transporter function in vivo. Imaging is an import diagnostic tool in clinics and is a novel t...

Nevertheless, obstruction rarely can occur without hydronephrosis, when the ureter and renal pelvis are encased in a fibrotic process and unable to expand. In contrast, mild dilation of the collecting system of no functional significance is not unusual. Even obvious hydronephrosis in some cases may not be associated with functional obstruction [70]. Diuresis renography is helpful when the funct...

PURPOSE The objectives of the study were to use the International Atomic Energy Agency (IAEA) software package for the analysis of scintigraphic renal dynamic studies to obtain values of curve parameters and excretory parameters in children with hydronephrosis and to validate the reliability of these numerical outputs by comparing with values established by consensus reports. PATIENTS AND MET...

In renovascular hypertension adaptive mechanisms in the poststenotic kidney are a probable cause of the 20 to 25% false-negative findings during rapid sequence urography or [123I]o-iodohippurate renography. We blocked the renin-angiotensin system in an effort to increase the yield of these diagnostic procedures. Chronically instrumented, salt-depleted conscious dogs were used in which a light (...