BACKGROUND The economic impact of therapeutic non-adherence in chronic diseases has rarely been examined using qualitative standards for economic evaluation. This study illustrates the impact of non-adherence on the cost utility of renal transplantation versus haemodialysis from the societal perspective and examines the scope for adherence-enhancing interventions. METHODS Long-term costs and ...

Background Acute liver failure (ALF) is a serious condition characterized by sudden dysfunction, jaundice and hepatic encephalopathy. Its mortality rate of approximately 80% underscores the urgent need for effective treatments. Supportive extracorporeal therapies (SET), which temporarily support function remove toxins, have shown promise in improving outcomes acute (ALF). The aim this study was...

Abstract. Kidney transplantation is recognized as the optimal method of end-stage kidney disease treatment, but chronic renal allograft rejection remains an unresolved issue and leads to transplanted organ function loss. Recent studies show positive effects stem cell injections in a variety diseases, including transplantation.
 The present study aimed analyze first experience umbilical cor...

Liver-kidney transplantation in patients with primary hyperoxaluria type 1 (PH1) and a high systemic oxalate load is often complicated by oxalate deposition in the renal allograft and loss of renal function. Intensive pre- and post-operative haemodialysis (HD) cannot completely prevent rises in plasma oxalate levels during transplantation because of rebound from saturated oxalate stores. Contin...

BACKGROUND AND PURPOSE Mycophenolate mofetil (MMF) in combination with cyclosporine or tacrolimus prevents acute rejection and chronic allograft failure in renal transplantation in Western countries. We began to add low-dose MMF to primary cyclosporine immunosuppressive therapy in renal transplantation at the Department of Surgery of National Taiwan University Hospital in 1998. This study compa...

SINCE the introduction of cyclosporine (CsA)-steroid therapy for our liver transplant recipients in March 1980, the survival rates have increased significantly as shown in Fig 1. The effective and relatively safe immunosuppression provided by CsA is undoubtedly the most important factor in the improved success rate. l N~'phrotoxicity is a troublesome side effect of CsA. The distinction between ...

We examined the survival time and costs of therapy for patients with end-stage renal disease. A computer simulation model of the current system was constructed to estimate the cost-effectiveness of home and center hemodialysis and live related as well as cadaver donor renal transplantation. Analysis of the simulation showed that live related donor transplantation was the least costly and had th...

background: today, renal disease is one of the major worldwide health problems. it has a high prevalence, which increases 8% annually. incidence of renal disease and treatment techniques can affect the quality of life, health status and social roles of patients. the aim of the current study was to determine the quality of life of dialysis and kidney transplant patients and compare it to healthy...