A high salt diet has been shown to increase renal mass of intact rats, although the mechanism by which this occurs has not been investigated. We used Dahl rats that are sensitive (DS) or resistant (DR) to the hypertensinogenic effect of salt to examine changes in renal size and composition caused by a high salt diet. Renal index, deoxyribonucleic acid (DNA), protein, water content, protein/DNA ...

BACKGROUND Although the American Association of the Surgery for Trauma Organ Injury Scale is the gold standard for staging renal trauma, it does not address characteristics of perirenal hematomas that may indicate significant hemorrhage. Angiographic embolization has become well established as an effective method for achieving hemostasis. We evaluated two novel radiographic indicators--perirena...

BACKGROUND Diabetes is a chronic disease characterized by impaired fasting blood glucose that leads to disturbances in various organs. In this study, we evaluated relationships between tumor size and grade in a population of diabetic and non-diabetic patients with renal cell carcinoma. MATERIALS AND METHODS Between 2007-2013, in our clinic radical nephrectomy performed to 310 patients for ren...

Objective: To accurately describe the growth of human renal clear cell carcinoma. In our earlier research, the growth model of renal tumors is linear and is not accurate. A better growth model is needed. Methods: There patients under surveillance for more than ten years with renal tumors were analyzed. Tumor size and time were recorded in each observation. Curve fitting of renal tumor growth wa...

The present study was designed to determine the effects of shock wave voltage (kV) on lesion size and renal function induced by shock wave lithotripsy (SWL) in the 6- to 8-wk-old pig. Each SWL-treated pig received 2000 shock waves at 12, 18, or 24 kV to the lower pole calyx of one kidney. A group of sham SWL pigs served as time controls. Bilateral GFR, renal plasma flow (RPF), and para-aminohip...

Renal blood flow was elevated in convalescent burn patients shortly before discharge (992 +/- 112 mL/min/sq m in burn patients vs 551 +/- 37 mL/min/sq m in normal subjects; mean +/- SE). Autopsy studies demonstrated that renal enlargement was a constant feature of patients after a prolonged hospital course; the kidneys of 28 patients who died after 60 days of hospitalization weighed 241 +/- 10 ...

BACKGROUND Renal impairment is common in patients with atherosclerotic renovascular disease (ARVD), but its pathogenesis is uncertain. This study investigated whether any relationship existed between renal function and the severity of proximal renal arterial lesions in patients with ARVD. METHODS A cohort of 71 patients had creatinine clearance measured at the time of digital subtraction angi...

The aim of this study was to check the relationship between the density of urinary EVs, their size distribution, and the progress of early renal damage in type 2 diabetic patients (DMt2). Patients were enrolled to this study, and glycated hemoglobin (HbA1c) below 7% was a threshold for properly controlled diabetic patients (CD) and poorly controlled diabetic patients (UD). Patients were further...

Background and Objectives: RCC is one of the most common genitourinary cancers. Accurate prediction of prognosis would be valuable for adjuvant trial design, counseling and effectively scheduling follow up visits. P53 is a tumor suppressor gene that expresses a protein that involved in both cell-cycle ar...

objective(s): the wide scale use of zinc oxide nanoparticles (zno nps) in the consumer market world makes human beings more prone to the exposure to zno nanoparticles and its adverse effects. therefore, the aim of the present study is to assess renal toxicity potential of zno and polyethylene glycol coated zno nanoparticles in rat.materials and methods: co-precipitation chemical method was used...