Renal insufficiency is a serious healthcare problem. The Iodine renal toxicity and the link of Gadolinium to Nephrogenic Systemic Fibrosis makes conventional imaging of the severely malfunctioning kidneys not safe for the patient. Functional imaging in nephrology where anatomy and physiology are jointly considered, is a necessary diagnostic tool in patients with renal insufficiency in general a...

Response to Letter Regarding Article, “Proteinuria, but Not eGFR, Predicts Stroke Risk in Chronic Kidney Disease: Chronic Renal Insufficiency Cohort Study” We thank Dr Tsuda for the interest in our article. Biomarkers collected as part of the Chronic Renal Insufficiency Cohort (CRIC) study will help us in this important next step exploring the mechanistic pathways related to cerebrovascular dis...

The most severe complication of yttrium-90 therapy is gastrointestinal ulceration caused by extrahepatic dispersion of microspheres. Standard pretreatment planning requires extensive angiographic evaluation of the hepatic circulation and embolization of hepatoenteric collaterals; however, in patients with severe renal insufficiency, this evaluation may lead to acute renal failure. In order to m...

Paracetamol has always been regarded as a useful and safe drug. The risk of toxicity with repeated supratherapeutic paracetamol is an underrecognised condition. We report on a 12-month-old boy who presented with hepatotoxicity, disseminated intravascular coagulation and persistent renal insufficiency 4 days after repeated ingestion of a supratherapeutic dosage of paracetamol. To the best of our...

We aimed to investigate differences in clinical manifestations and outcomes between adult and child patients with Henoch-Schönlein purpura (HSP), and to analyze the factors associated with poor prognosis for HSP nephritis. This retrospective 10-yr study enrolled 160 patients with HSP who visited Severance Hospital. Purpura was mostly detected in lower extremities, but purpura in upper extremiti...

INTRODUCTION Chronic kidney disease (CKD) affects all age groups, and its prevalence has increased during recent years. CKD is divided into six stages, according to the renal function of patients: 1. Normal renal function without kidney damage; 2. Kidney damage with normal renal function; 3. Mild renal insufficiency; 4. Moderate renal insufficiency or lab tests failure; 5. Severe renal insuffic...