BACKGROUND The effects of propofol, remifentanil, and their combination on phrenic nerve activity (PNA), resting heart rate (HR), mean arterial pressure (MAP), and nociceptive cardiovascular responses were studied in rabbits. METHODS Basal anesthesia and constant blood gas tensions were maintained with alpha-chloralose and mechanical ventilation. PNA, HR, MAP, and maximum changes in HR and MA...

PURPOSE The study aimed to assess the combined effects of parecoxib with three different doses of remifentanil and its effect on the stress and cough responses following tracheal extubation under general anesthesia. METHODS A total of 120 patients with American Society of Anesthesiologists (ASA) scores of I or II, undergoing selective thyroidectomy with total intravenous anesthesia (propofol-...

BACKGROUND Emergence from anaesthesia and tracheal extubation can be associated with hyperdynamic circulatory responses. We examined the effects of maintaining a remifentanil infusion on recovery profiles such as coughing and cardiovascular responses after general anaesthesia. METHODS Forty patients undergoing endoscopic sinus surgery under general anaesthesia using total i.v. anaesthesia (pr...

Comparison of the effects Tranexamic Acid and Remifentanil on Reduction Intraoperative Postoperative Hemorrhage during Dacriocystorhynostomy

Comparison of the Effects Ketamine-Remifentanil with Ketamine-Propofol on Pain, Agitation and Hemodynamic Changes during Closed Reduction Nasal Fracture

In the current issue of the British Journal of Anaesthesia, Shin and colleagues report that propofol used for the maintenance of general anaesthesia may prevent remifentanilinduced hyperalgesia. In their study, a comparison of propofol and sevoflurane combined with either high dose or low dose of remifentanil for the maintenance of general anaesthesia in breast cancer surgery was conducted. The...

Background It is speculated that opioid-free anesthesia may provide adequate pain control while reducing postoperative opioid consumption. However, there currently no evidence to support the speculation. The authors hypothesized balanced anesthetic with dexmedetomidine reduces opioid-related adverse events compared remifentanil. Methods Patients were randomized receive a standard either intraop...

BACKGROUND Remifentanil is an effective drug for protecting against adverse haemodynamic responses to tracheal intubation. We compared the haemodynamic responses during anaesthesia induction between continuous intravenous (IV) infusion and two bolus injections of remifentanil. METHODS This prospective, randomised, open-label, single-centre study included patients with American Society of Anes...

We have had this study to evaluate the clinical profile of target-controlled infusion-based anesthesia using remifentanil and propofol. 116 ASA I-II patients undergoing elective laparoscopic cholecystectomy (LCH) were enrolled. TCI Remifentanil was set at 8 micrograms. L - 1 as target and TCI propofol at 4 mcg/ml throughout the whole procedure. The hemodynamics during induction of anesthesia an...