Background and purpose: Quantitative analysis of brain atrophy may be useful in differentiating Parkinson’s Disease (PD) from Progressive Supranuclear Palsy (PSP) and parkinsonian variant of Multiple System Atrophy (MSA-P); the aim of this study was to identify the volumetric differences of subcortical structures in patients with PD, PSP and MSA-P using a novel and validated fully-automated who...

People with Parkinson’s disease (PD) have difficulty performing dual tasks or simultaneous movements, even if the same movements can be easily performed individually. This has particular significance clinically, as for example falling injuries may occur if care is not taken to perform tasks one at a time. We investigated whether this difficultyx results from impaired dopamine-modulated connecti...

Background: In Parkinson’s disease (PD), neurodegenerative changes have been observed in autonomic pathways involving multiple organ systems. We explore pupillary and cardiac autonomic measures as physiological manifestations of PD neurodegeneration. Methods: Pupil measures (pupillary unrest (spontaneous changes of pupil diameter in darkness), constriction velocity and redilation velocity) were...

Background: Over the last decades, increasing knowledge about the genetic architecture of Parkinson’s disease(PD) has provided novel insights into the pathogenesis of the disorder. Recently, several studies in different populations have found a strong association between idiopathic PD and the single-nucleotide polymorphism (SNP) rs356219, which is located in the 30UTR of the SNCA gene. In this ...

Background: The mechanisms underlying the development of impulse control disorders (ICDs) like compulsive gambling, buying, sexual, and eating behaviors in Parkinson’s disease (PD) are debated. We assessed whether allelic variants of dopamine D2 receptors (DRD2), catechol-O-methyltransferase (COMT) and dopamine transporter (DAT) were associated with the development of ICDs in PD. Method: We enr...

Sleep difficulty is one of the hallmarks of menopause. Following recent studies showing no cardiac benefit and increased breast cancer, the question of indications for hormonal therapy has become even more pertinent. Three sets of sleep disorders are associated with menopause: insomnia/depression, sleep disordered breathing and fibromyalgia. The primary predictor of disturbed sleep architecture...

Nearly all patients with Parkinson’s disease (PD) experience gait problems, often already in early disease stages, with clear worsening as the disease progresses. It would be helpful to have a simple and objective tool to quantify gait, both in the laboratory setting and in the patient’s own home environment. This could facilitate clinical decision making, or can be used as outcome measure in c...

Objective: The purpose of this study was to evaluate the effect of attachment-based interventions on females suffering from eating related disorders. The study method was experimental with a pretest-posttest control group. The study sample included 32 elementary school female students with eating disorders, obesity problems, and attachment disorders. Sampling method was purposive.  Methods: ...

purpose: to determine the effectiveness of group supportive psychotherapy by interpersonal psychotherapy method in reducing anxiety of addicts who are quitting. materials and methods: among rehabilitation centers for drug abusers in isfahan, a total of 30 addicted patients in the process of withdrawal were selected by convenience sampling, and randomly divided into two groups of 15 people as te...

AMA Foryś E, Baran A, Dziurdzia et al. Are menstrual disorders in adolescent girls related to metabolic disorders?. Pediatric Endocrinology Diabetes and Metabolism. 2023. doi:10.5114/pedm.2023.125364. APA Foryś, E., Baran, A., Dziurdzia, Jarosz-Wójcik, Matusik, P., & Gawlik, A. (2023). https://doi.org/10.5114/pedm.2023.125364 Chicago Elżbieta, Adrianna Aleksandra Ewelina Paweł Aneta Ryszard Tom...