the ponseti method is a safe and effective treatment for congenital clubfoot, and radically decreases the need for extensive corrective surgery. but a group of patients will still present with under corrected residual equinovarus deformities despite the proper use of the ponseti method. about 25% of operated clubfeet will develop recurrence or show a marked residual deformity (recurrent clubfoo...

purpose: to report an unusual ocular presentation of a relapse of acute lymphoblastic leukemia. case report: a 9-year-old girl presented with a subconjunctival mass and ipsilateral preauricular lymphadenopathy. she had history of acute lymphoblastic leukemia (all) in remission but had a normal blood cell profile. because of corneal dellen formation and enlargement of the mass over a 2-week peri...

OBJECTIVE To compare the rate of relapse as a function of antipsychotic treatment (monotherapy vs. polypharmacy) in schizophrenic patients over a 2-year period. METHODS Using data from a multicenter cohort study conducted in France, we performed a propensity-adjusted analysis to examine the association between the rate of relapse over a 2-year period and antipsychotic treatment (monotherapy v...

BACKGROUND Relapse is common in schizophrenia, and seriously impacts patients' quality of life and social functioning. Many factors have been identified that may potentially increase the risk of relapse. This study was designed to investigate the relapse rate in the year following hospital discharge among Chinese patients with schizophrenia in the naturalistic condition, and to explore possible...

Background: To assess the direct cost of relapse, the predictors of relapse, and the role of prior relapse in the treatment of schizophrenia in the United States. Methods: Data were drawn from a prospective, observational, noninterventional study of schizophrenia in the United States (7/1997-9/2003). Patients with and without relapse in the prior 6 months were compared on total direct mental he...

OBJECTIVE To determine the frequency, time interval to relapse and the possible risk factors for relapse in multibacillary (MB) leprosy after 1 year's treatment with the standard multi-drug therapy (MDT). MATERIALS AND METHODS Smear positive MB patients treated with MDT for 1 year were enrolled in a prospective relapse study between 1999 and 2005 at the Leonard Wood Memorial Center for Lepros...

Background/Aims In Taiwan, due to budget limitations, the National Health Insurance only allows for a limited period of biologics use in treating moderate to severe Crohn's disease (CD). We aimed to access the outcomes of CD patients following a limited period use of biologics, specifically focusing on the relapse rate and remission duration; also the response rate to second use when applicable...

BACKGROUND AND OBJECTIVES Visceral leishmaniasis (VL) is a common complication in AIDS patients living in Leishmania-endemic areas. Although antiretroviral therapy has changed the clinical course of HIV infection and its associated illnesses, the prevention of VL relapses remains a challenge for the care of HIV and Leishmania co-infected patients. This work is a systematic review of previous st...

Background: Relapse in leukemic patients is considered as a major cause of treatment failure and a decrease in patient survival rate. This study was conducted to determine the survival rate of patients with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) based on their relapse status. Materials and Methods: This retrospective cohort study was performed on a total of 243 case...