نتایج جستجو برای: reference panel

تعداد نتایج: 352935  

2014
Arpan Acharya Salil Vaniawala Parth Shah Rabindra Nath Misra Minal Wani Pratap N. Mukhopadhyaya

Human Immunodeficiency Virus-1 (HIV-1) drug resistance genotyping assay is a part of clinical management of HIV-1 positive individuals under treatment with highly active antiretroviral therapy (HAART). Routine monitoring of drug resistance mutations in resource limited settings like India is not possible due to high cost of commercial drug resistance assays. In this study we developed an in-hou...

Journal: :American journal of human genetics 2009
Lucy Huang Yun Li Andrew B Singleton John A Hardy Gonçalo Abecasis Noah A Rosenberg Paul Scheet

A current approach to mapping complex-disease-susceptibility loci in genome-wide association (GWA) studies involves leveraging the information in a reference database of dense genotype data. By modeling the patterns of linkage disequilibrium in a reference panel, genotypes not directly measured in the study samples can be imputed and tested for disease association. This imputation strategy has ...

2011
Rongbao Gao Yan Gao Leying Wen Ming Shao Shumei Zou Changgui Li Lei Yang Xiyan Li Wei Wang Yuelong Shu

BACKGROUND Reverse transcription PCR (RT-PCR) and real time RT-PCR (rRT-PCR) have been indispensable methods for influenza surveillance, especially for determination of avian influenza. The movement of testing beyond reference lab introduced the need of quality control, including the implementation of an evaluation system for validating personal training and sample proficiency testing. METHOD...

Journal: :Journal of clinical pathology 1983
E M Supran J Craske R J Hart J B Kurtz J V Parry S J Skidmore P S Gardner

The results of a field trial of a joint DMRQC/Organon ELISA kit for the detection of hepatitis A IgM antibody are reported. The participating laboratories were asked to use the kit to test a panel of 360 specimens consisting of duplicate coded samples of 180 sera. The panel was also tested by MACRIA in the Virus Reference Laboratory, Colindale. The ELISA was shown to be specific and sensitive g...

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