Recent ly , a cloned DNA probe l a b e l l e d wi th m e t a l c h e l a t o r s ( d i ethylentriamine pentaacetate, DTPA) was used in a dot-blot hybridization assay for the non-radioactive detection of down to 1 attomol target DNA by europium time-resolved fluorometry (1). We now report modifications of the procedure which led to a more than tenfold increase in sensitivity. A DTPA-labelled, HB...

BACKGROUND Postgraduate medical education prepares residents for delivery of high quality patient care during training as well as for later practice, which makes high quality residency training programs crucial to safeguard patient care. Healthy learning climates contribute to high quality postgraduate medical education. In several countries, modernization of postgraduate medical education has ...

BACKGROUND Functional brain images such as Single-Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET) have been widely used to guide the clinicians in the Alzheimer's Disease (AD) diagnosis. However, the subjectivity involved in their evaluation has favoured the development of Computer Aided Diagnosis (CAD) Systems. METHODS It is proposed a novel combination of ...

THE 1990s HAVE USHERED in an era of rapid change, both in America's employ­ ment of its military forces and in its sense of its defense needs for the next century. A revo lu tion in military affairs (RMA) looms: some ob serv ers claim that De sert Storm's stra ­ te gic air cam paign her alded ad vances in tech ­ nol ogy and doctrine that will funda men tally re shape future warfare. Today, the ...

Abs t rac t -The phys ica l s ize of inductors in resonant converters was examined i n terms o f inductor t o transformer s i z e rat io . F o l l o w i n g the general d i scuss ion o f the i s s u e , the inductor s i z e i n ser i e s resonant DC-DC converter i s examined i n deta i l . It i s shown that the inductor t o transformer s i z e rat io i s a funct ion of the peak v o l t a g e o ...

In Ve ron ica Ro dri guez-Blanco’s thought ful and im por tant ar ti cle, “Rea sons in Ac tion v Trig ger ing Rea sons: A Re ply to Enoch on Rea son-Giv ing and Le gal Normativity,” she ex plores with great care the na ture of rea son-giv ing, in con nec tion with chal leng ing Da vid Enoch’s in flu en tial re cent work on rea son-giv ing and the law. While Ro dri guez-Blanco’s ar ti cle makes ...

Ab stract It has been sug gested since the be gin ning of pre his toric re search in the Lev ant, that the Natufians used stone mor tars for the pro cess ing of ce re als and/or other veg e tal re sources, though di rect ev i dence is still lack ing. A re cent de tailed study of more than 100 bed rock mor tars and cupmarks in di cates that, a) they are found in many Late Natufian sites, re gard...

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The branch-and-bound algorithm is stated in general i ty, and i l l us t ra ted by two applications, unidirect ional graph search, and reducing a sparse matrix to i t s minimal band form. The algorithm is then generalised to mult iple par t i t ions , applied to bid i rect ional graph searching for both heurist ic and non-heuristic searches, and further extended to graph searches and problem so...

The structural determination of the Pt(111)c(5x√3)rect.-CO phase formed by 0.6 ML of adsorbed CO has been undertaken using scanned-energy mode photoelectron diffraction utilising the two distinct components of the C 1s photoemission peak. Earlier assignments of CO to atop and bridge sites have been confirmed as well as the respective 2:1 ratio of these assignments. Additionally, quantitative lo...