visceral leishmaniasis (vl) is a zoonotic disease caused by leishmania species. dogs are considered to be the main reservoir of vl. a number of methods and antigen-based assays are used for the diagnosis of leishmaniasis. however, currently available methods are mainly based on direct examination of tissues for the presence of parasites, which is highly invasive. a variety of serological tests ...

background: interleukin-27 is a heterodimeric cytokine belonging to il-12 and il-23 families, secreted  by antigen presenting cells( apcs ) .the il-27 is composed of 2 subunits: epstein-barr virus induced gene 3 (ebi3) and p28. il-27 is an anti-inflammatory cytokine which has an inhibitory effect on th17 population and suppress the il-17 expression. it is suggested that il-27 could be a potent ...

white spot syndrome virus (wssv) is a highly pathogenic and prevalent virus affecting shrimp culture worldwide including iran. in the present study, a pair of primers was designed according to the sequence of vp 28 gene of wssv in the genbank. vp28 gene from an iranian wssv isolate (irvp28) was cloned, sequenced and expressed in escherichia coli bl21(de3) strain in order to produce vp28 protein...

Bir kentte fiziksel, çevresel, sosyal ve ekonomik anlamda ortaya çıkabilecek tüm sorunlarla mücadelede kentin paydaşları ile ortaklaşa hareket edilmesi, kenti daha dirençli hale getirebileceği gibi kendilerini güvende hissedebilecekleri bir kente dönüştürecektir. Bu durum her şeyden önce belediyelerde katılımcı modelin benimsenmesi paydaş katılımına önem veren yönetim anlayışıyla mümkündür. çal...

Bu çalışma mülteci kamplarındaki göç ve yardım çalışmalarını uluslar arası bir STK olan İnsani Yardım Vakfı’nın (İHH) Bangladeş-Cox’sBazar çalışmalar üzerinden değerlendirmeyi amaçlamaktadır. kapsamda İHH’nınCox’sBazar’daki faaliyetleri incelenmiştir. faaliyetler, İHH yetkilileri ile yapılan görüşmeler, alanda bazı mültecilerle yüz yüze doküman incelemesi sırasında gerek Türkiye’de gerekse katı...

UNLABELLED The ability to monitor tumor responses during prodrug activation gene therapy and other anticancer gene therapies is critical for their translation into clinical practice. Previously, we demonstrated the feasibility of noninvasive in vivo imaging with 131I-5-iodo-2'-fluoro-1-beta-D-arabinofuranosyluracil (131I-FIAU) for monitoring herpes simplex virus type 1 thymidine kinase (HSV1-tk...

background: the over-expression of recombinant proteins in large amount is important for production of therapeutic proteins and structural study. there are several systems for expression of recombinant proteins. one of the most relevant expression systems is escherichia coli (e. coli). although this organism has many advantages, most of recombinant proteins expressed in e. coli hosts form inclu...

background: saccharomyces boulardii (s. boulardii) is the best known probiotic yeast. the genetic engineering of this probiotic strain requires the availability of appropriate mutants to accept various gene constructs carrying different selection markers. as the auxotrophy selection markers are under focus, we have generated a ura3 auxotroph mutant of s. boulardii for use in further genetic man...