نتایج جستجو برای: recombinant protein p23
تعداد نتایج: 1297760 فیلتر نتایج به سال:
objective: escherichia coli o157:h7 is a gram-negative rod-shaped bacterium. e coli o157:h7 is an enterohemorrhagic (ehec) strain of the bacterium escherichia coli and a cause of foodborne illness. infection often leads to bloody diarrhea by producing a toxin called shiga toxin, which damages the intestines, and occasionally leads to kidney failure, especially in young children and elderly peop...
background and objectives: brucellosis is an important health problem in developing countries and no vaccine is available for the prevention of infection in humans. because of clinically infectious diseases and their economic consequences in human and animals, designing a proper vaccine against brucella is desirable. in this study, we evaluated the immune responses induced by a designed recombi...
CD40 is a 45-kDa glycoprotein member ofthe tumor necrosis factor receptor (TNFR) family expressed on B cells, thymic epithelial cells, dendritic cells, and some carcinoma cells. The unique capacity of CD40 to trigger immunoglobulin isotype switching is dependent on the activation of protein-tyrosine kinases, yet CD40 possesses no kinase domain and no known consensus sequences for binding to pro...
Background: Interferon beta is one of the most important members of group I interferons and is the main drug for multiple sclerosis treatment. Interferon beta has short half life and this compels patients to make frequent use of medicine. According to its clinical usage there is broad effort to improve translation level and protein production. There are several important factors which effect pr...
Background: Recombinant proteins overexpressed in E. coli are usually deposited in inclusion bodies. Cysteines in the protein contribute to this process. Inter- and intra- molecular disulfide bonds in chitinase, a cysteine-rich protein, cause aggregation when the recombinant protein is overexpressed in E. coli. Hence, aggregated proteins should be solubilized and allowed to refold to obtain nat...
Chlamydia trachomatis is one of the main causes of Sexually Transmitted Diseases (STDs) such as prostatitis and epididymitis in men and cervicitis, endometriosis, vaginitis and ureogenital tract infections in women. Serological tests with sensitivities related to specific antigens are commonly used as routine laboratory tests for diagnosis of Chlamydia. In this research the Chlamydia Major O...
Background: Improving the performance of HIV diagnosis assays is one of the most important ways to reduce HIV transmission. Because of the high mutation rate of HIV, it is critical to use the conserved proteins to develop diagnostic immunoassay methods. Because integrase is one of the most conserved proteins of HIV, it may be a good target for this purpose. In this paper cloning, purification a...
Background and purpose: Rapid emergence of traditional antibiotic-resistant pathogens is one of the most important global challenges in medical sciences. To this end, substitution of current antibiotics with strong antimicrobial peptides could be of great benefit. Materials and methods: In this study, the DNA sequence encoding dermaseptin B1 (DrsB1) antimicrobial peptide derived from Phyllomed...
The recombinant antibodies RB712 and RB713 detect by ELISA the Drosophila melanogaster Spargel protein (or GCH) fused to a GST protein.
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