نتایج جستجو برای: recombinant momp protein

تعداد نتایج: 1297357  

Journal: :iranian journal of parasitology 0
p shahbazi p shayan e ebrahimzadeh s rahbari

background: cryptosporidium parvum is a parasitic protozoan that functions as important causa­tive agent of diarrhea in human and animals. the host's immune response to surface anti­gens of c. parvum has been previously demonstrated. in this respect, the role of humoral immu­nity in the development of host protective immunity against this protozoon has been well demon­strated. methods: the effe...

Journal: :iranian journal of basic medical sciences 0
hossein fahimi department of genetics, faculty of biological sciences, tarbiat modares university, tehran, iran 2 department of cellular and molecular biology, islamic azad university, pharmaceutical sciences branch (iaups), tehran, iran hossein allahyari department of immunology, faculty of medical sciences, tehran medical university, tehran, iran zuhair m hassan department of immunology, faculty of medical sciences, tarbiat modares university, tehran, iran majid sadeghizadeh department of genetics, faculty of biological sciences, tarbiat modares university, tehran, iran

objective(s): production of a recombinant and immunogenic antigen using dengue virus type-3 envelope protein is a key point in dengue vaccine development and diagnostic researches. the goals of this study were providing a recombinant protein from dengue virus type-3 envelope protein and evaluation of its immunogenicity in mice. materials and methods: multiple amino acid sequences of different i...

Journal: :Infection and immunity 2005
Sukumar Pal Ellena M Peterson Luis M de la Maza

BALB/c mice were vaccinated by the intramuscular (i.m.) and subcutaneous (s.c.) routes with a native preparation of the Chlamydia trachomatis mouse pneumonitis (MoPn) major outer membrane protein (MOMP), using Montanide ISA 720 and CpG-1826 as adjuvants. A negative control group was immunized with ovalbumin and the two adjuvants, and a positive control group was immunized intranasally (i.n.) wi...

Journal: :iranian journal of pharmaceutical research 0
hamid reza heidari department of pharmaceutical biotechnology, faculty of pharmacy, shahid beheshti university of medical sciences, tehran, iran mojgan bandehpour cellular and molecular biology research center, shahid beheshti university of medical sciences, tehran, iran department of biotechnology, faculty of medicine, shahid beheshti university of medical sciences, tehran, iran hossein vahidi department of pharmaceutical biotechnology, faculty of pharmacy, shahid beheshti university of medical sciences, tehran, iran jaleh barar research centre for pharmaceutical nanotechnology, tabriz university of medical sciences, tabriz, iran bahram kazemi shahid beheshti university of medical sciences hossein naderi-manesh department of biophysics, faculty of biological sciences, tarbiat modares university, tehran, iran

molecular farming has been considered as a secure and economical approach for production of biopharmaceuticals. human tnf related apoptosis inducing ligand (trail) as a promising biopharmaceutical candidate has been produced in different expression hosts. however, little attention has been paid to molecular farming of the trail in spite of numerous advantages of plant expression systems. theref...

Journal: :archives of clinical infectious diseases 0
mojgan bandehpour cellular and molecular biology research center, shahid beheshti university, m.c., tehran, ir iran narges abdali islamic azad university, research and science campus, tehran, ir iran farzaneh sadeghi department of biology, shahid beheshti university, m.c., tehran, ir iran kazem parivar islamic azad university, research and science campus, tehran, ir iran zarrin sharifnia cellular and molecular biology research center, shahid beheshti university, m.c., tehran, ir iran hossein ryahi department of biology, shahid beheshti university, m.c., tehran, ir iran

background brucellosis is an important cosmopolitan infection disease caused by organisms belonging to the genus brucella. the cgt gene (cyclic β-1, 2 glucan transporter gene) is a virulent factor in brucella genus. the present study was conducted with the aim of cloning and expression of brucella cgt gene. materials and methods brucella melitensis cgt gene was amplified from extracted chromoso...

زیبایی, سعید, حق‌پرست, ، علیرضا , دوستی, محمد , طهمورث‌پور, مجتبی , نصیری, ، محمدرضا ,

     Foot-and-mouth disease (FMD) is an extremely infectious and occasionally fatal viral disease with a rapid onset and a short course that affects cloven-hoofed animals and results in considerable financial losses. For this reason, availability of more reliable and efficient vaccines against Foot-and-mouth disease virus (FMDV) is felt as a necessity. The purpose of this study is to develop a ...

Journal: :iranian biomedical journal 0
مصیب رستمیان mosayeb rostamian سید جعفر موسوی seyed jafar mousavy فیروز ابراهیمی firouz ebrahimi سید ابوالقاسم قدمی seyyed abolghasem ghadami نادر شیبانی nader sheibani محمد ابراهیم مینایی mohammad ebrahim minaei محمد علی عارف پور ترابی

background: recently, botulinum neurotoxin (bont)-derived recombinant proteins have been suggested as potential botulism vaccines. here, with concentrating on bont type e (bont/e), we studied two of these binding domain-based recombinant proteins: a multivalent chimer protein, which is composed of bont serotypes a, b and e binding subdomains, and a monovalent recombinant protein, which contains...

Firouz Ebrahimi, Mohammad Ali Arefpour Torabi, Mohammad Ebrahim Minaei, Mosayeb Rostamian, Nader Sheibani, Seyed Jafar Mousavy, Seyyed Abolghasem Ghadami,

Background: Recently, botulinum neurotoxin (BoNT)-derived recombinant proteins have been suggested as potential botulism vaccines. Here, with concentrating on BoNT type E (BoNT/E), we studied two of these binding domain-based recombinant proteins: a multivalent chimer protein, which is composed of BoNT serotypes A, B and E binding subdomains, and a monovalent recombinant protein, which contains...

Ali Mohammad Ahdi Fatemeh Malaei Hussein Honari Mahdi Hesaraki Mohammad Sadraeian Mojtaba Saadati, Shahram Nazarian

Background: Recombinant vaccine technology is one of the most developed means in controlling infectious diseases. However, an effective vaccine against Shigella is still missing. Objective: To evaluate recombinant IpaC protein of Shigella as a vaccine candidate. Methods: In this study we cloned IpaC gene into an expression vector in prokaryotic system. The protein expression was evaluated by SD...

Journal: :Cold Spring Harbor perspectives in biology 2013
Tom Bender Jean-Claude Martinou

Although mitochondria are usually considered as supporters of life, they are also involved in cellular death. Mitochondrial outer membrane permeabilization (MOMP) is a crucial event during apoptosis because it causes the release of proapoptotic factors from the mitochondrial intermembrane space to the cytosol. MOMP is mainly controlled by the Bcl-2 family of proteins, which consists of both pro...

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