ROC curve analysis is often applied to measure the diagnostic accuracy of a biomarker. The analysis results in two gains: diagnostic accuracy of the biomarker and the optimal cut-point value. There are many methods proposed in the literature to obtain the optimal cut-point value. In this study, a new approach, alternative to these methods, is proposed. The proposed approach is based on the valu...

Purpose This study evaluated the cytokine levels in unilateral tear samples from both sides in patients with pediatric lacrimal duct obstruction. Methods Fifteen cases of unilateral lacrimal duct obstruction (mean, 26.9 ± 28.7 months old) were enrolled in this study. Tear samples were collected separately from the obstructed side and the intact side in each case before surgery, which was perf...

PURPOSE Prostate biopsy is used to confirm the prostate cancer. Although first biopsy result was benign, repeat biopsy is recommended for the patient who has higher risk of prostate cancer. In this study, we investigated the PSA change ratio (post-biopsy PSA to baseline PSA) whether it could be predictive factor of prostate cancer and helpful when decided to perform repeat biopsy. MATERIALS A...

between stenosis and NWI measurements (r=0.59, p<0.001). Fig 2. ROC curves of stenosis measurement for identifying plaque features. Fig 3. Subject (73 y/o male) with right internal carotid arterial stenosis = 15% seen on the CE MRA MIP (right side); while hemorrhage (arrow) and ruptured fibrous cap (arrowhead) were identified on the TOF and T1W images. Four continuous cross-sectional images are...

BACKGROUND To compare the diagnostic accuracy of two continuous screening tests, a common approach is to test the difference between the areas under the receiver operating characteristic (ROC) curves. After study participants are screened with both screening tests, the disease status is determined as accurately as possible, either by an invasive, sensitive and specific secondary test, or by a l...

Material and Method : A prospective study of analysis of 100 cases (50 ascites and 50 pleural fluids) was carried out over a period of 6 months. In all these cases, clinical diagnosis was established after clinical examination and appropriate investigations. The fluid and serum levels of protein, albumin, LDH and cholesterol were determined and various ratios were obtained. The statistical anal...

The Visual Concept Detection Task (VCDT) of ImageCLEF 2008 is described. A database of 2,827 images were manually annotated with 17 concepts. Of these, 1,827 were used for training and 1,000 for testing the automated assignment of categories. In total 11 groups participated and submitted 53 runs. The runs were evaluated using ROC curves, from which the Area Under the Curve (AUC) and Equal Error...