background : limited studies are available on the calculation of radiation exposure and its associated risks for people in contact with patients who have been treated with permanent prostate brachytherapy. in this study the changes in the radiation exposure were calculated in different stages of the bladder fullness in prostate seed brachytherapy. methods :magnetic resonance images of three pat...

PURPOSE In this work, the authors retrospectively compared the accumulated dose over the treatment course for stereotactic body radiation therapy (SBRT) of lung cancer for three patient setup strategies. METHODS Ten patients who underwent lung SBRT were selected for this study. At each fraction, patients were immobilized using a vacuum cushion and were CT scanned. Treatment plans were perform...

BACKGROUND Docetaxel is a widely active cytotoxic agent. The principal dose-limiting toxicities (DLTs) of the 3-weekly regimen are neutropenia and febrile neutropenia. Use of prophylactic granulocyte colony-stimulating factor (G-CSF) may allow higher doses of docetaxel to be administered with potentially greater anticancer efficacy. The objectives of this study were to determine the maximum tol...

OBJECTIVE To determine the dose-response relationship of excimer laser-generated 308-nm UV-B radiation for treating psoriasis. DESIGN Pilot study with a before-after design. SETTING A university dermatology service. PATIENTS Thirteen consecutive patients with at least 4 large, stable psoriasis plaques. INTERVENTIONS Excimer laser-generated 308-nm UV-B radiation was given to each of 4 pl...

BACKGROUND Radiation exposure can lead to detrimental effects in skin microcirculation. The precise relationship between radiation dose received and its effect on cutaneous perfusion still remains controversial. Previously, we have shown that hyperspectral imaging (HSI) is able to demonstrate long-term reductions in cutaneous perfusion secondary to chronic microvascular injury. This study chara...

INTRODUCTION This is an observational study and the aim is to evaluate the effect of dietary supplements based on Resveratrol, Lycopene, Vitamin C and Anthocyanins (Ixor®) in reducing skin toxicity due to external beam radiotherapy in patients affected by breast cancer. MATERIALS AND METHODS 71 patients were enrolled and they were divided in two different groups: a control group (CG) of 41 pa...

BACKGROUND Radiation therapy is performed as an adjuvant therapy when indicated following surgical resection of malignant tumors. However, radiation exposure induces acute or chronic dermatitis, depending on the radiation dose, interval, tissue volume, or irradiated area of the body. Radiation-induced skin ulcers and osteomyelitis of the underlying bone are intractable late-stage complications ...

Cutaneous tuberculosis (CTB) is the rarest form of (TB). CTB cases account for less than 1% all TB and about 15% extrapulmonary (EPTB) cases. rare even in communities where it endemic. has a variety manifestations can appear similar to other disease processes. Therefore, many clinicians have difficulty recognizing because known be great imitator. We present an unusual case which happened primar...

AIM OF THE STUDY Accurate skin dose assessment is necessary during breast radiotherapy to assure that the skin dose is below the tolerance level and is sufficient to prevent tumour recurrence. The aim of the current study is to measure the skin dose and to evaluate the geometrical/anatomical parameters that affect it. MATERIAL AND METHODS Forty patients were simulated by TIGRT treatment plann...

PURPOSE To determine the maximum tolerated dose (MTD) of continuous oral capecitabine plus oxaliplatin and pre-operative pelvic radiotherapy (XELOX-RT). PATIENTS AND METHODS Patients with clinically unresectable rectal cancer or for whom resection with histologically clear (R0) surgical margins was unlikely received continuous capecitabine (500-825 mg/m2 twice daily, 7 days/week), oxaliplatin...