AIMS To describe the clinical and pathological features of 10 further cases of fibroblastic polyps (FP), a recently described, distinctive type of colorectal mucosal polyp. METHODS AND RESULTS The patients were seven women and three men with ages ranging from 44 to 63 years. The lesions ranged in size from 2 to 4 mm. Eight of the polyps were located in the sigmoid colon. Five cases were assoc...

We have conducted a series of experiments to characterize the lesions that are precursors of cutaneous papillomas in SENCAR mice initiated with 7,12-dimethylbenz(a)anthracene (I)MIIA) and promoted with 12-0tetradecanoylphorbol-13-acetate (TPA). The first grossly detectable le sions at sites where papillomas subsequently developed were papules, slightly raised areas of skin ranging in diameter f...

introduction: few studies on benign soft tissue tumors of oral cavity have been conducted in an iranian population. the purpose of this study was to evaluate the prevalence of the benign soft tissue tumors of the oral cavity in three central pathology centers of rasht, iran. materials and methods: in this retrospective study, all benign soft tissue tumors of the oral cavity, were retrieved from...

Background: Gastric polyps are usually benign and asymptomatic lesions of the upper gastrointestinal tract observed in 1-8% of esophagogastroduodenoscopies (EGD). We had previously shared our endoscopy unit’s experience of gastric polyps between 2006 and 2012. The aim of this current study is to extend our previous results up to 2015 and to investigate any potential differences and changing tre...

AIMS A review of the literature indicated that only one case of serrated adenoma of the appendix has been recorded. The aim was to explore the possible occurrence of serrated adenomas of the appendix at the department of pathology, Karolinska Institute and University Hospital, Stockholm, Sweden. METHODS Between January 1993 and December 2003, 38 non-carcinoid, non-neoplastic, or neoplastic po...

Endometrial metaplasias and changes (EMCs) are conditions frequently overlooked and misdiagnosed. The aim of this review is to update current issues and provide a classification with a practical clinicopathological approach. Hormonal or irritative stimuli are the main inducing factors of EMCs, although some metaplasias have a mutational origin. EMCs vary from reactive, degenerative lesions to t...

Aims. To compare methylation profiles, protein expression, and microsatellite instability (MSI) of sporadic, HNPCC, and familial hyperplastic polyps (HPs). Methods. Methylation-specific PCR (MSP) and pyrosequencing assessed p16, MGMT, hMLH-1, MINT 1, and MINT 31 methylation. IHC (Immunohistochemistry) assessed Ki67, CK20, hMLH-1, hMSH-2, and hMSH-6 protein expression. MSI analysis was performed...

Our immunohistochemical study wants to be a contribution to clarifying the adenoma-carcinoma sequence and serrated pathway of colorectal carcinogenesis. Thus, we performed immunohistochemical analysis of hyperplastic polyps (HP), serrated adenomas (SA), and classical adenomas (tubular adenomas - TA and tubulovillous adenomas - TVA) and carcinomas developed from adenomas (CA) using expression of...