نتایج جستجو برای: rat liver mitochondria

تعداد نتایج: 604204  

Journal: :The Biochemical journal 1986
G S Denyer A L Kerbey P J Randle

Starvation of rats for 48 h increased the activity of PDH (pyruvate dehydrogenase) kinase 2.2-fold in extracts of liver mitochondria, 2.9-fold in PDH complex partially purified therefrom by fractional precipitation, and 5-fold in PDH complex partially purified by gel filtration on Sephacryl S-300. A protein fraction was separated from PDH complex in extracts of rat liver mitochondria by gel fil...

Journal: :American journal of physiology. Endocrinology and metabolism 2012
Wenche Jørgensen Peter Jelnes Kasper A Rud Lillian L Hansen Niels Grunnet Bjørn Quistorff

Impaired mitochondrial function is implicated in the development of type 2 diabetes mellitus (T2DM). This was investigated in mitochondria from skeletal muscle and liver of the Goto-Kakizaki (GK) rat, which spontaneously develops T2DM with age. The early and the manifest stage of T2DM was studied in 6- and 16-wk-old GK rats, respectively. In GK16 compared with GK6 animals, a decrease in state 3...

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