نتایج جستجو برای: ras 40
تعداد نتایج: 361655 فیلتر نتایج به سال:
In the present study, efficiency of Annona senegalensis fiber to remove crude oil from aqueous solution was evaluated. The (CAS), retted (RAS) and bleach (PFAS) were subjected sorption studies optimize their capacity. results revealed that sorbent water is related weight, contact time, initial concentration temperature sorption. It found out increase in weight led capacity 3.99-5.25g/g, 5.51-7....
Oncogenic mutations within RAS genes and inactivation of p53 are the most common events in cancer. Earlier, we reported that activated Ras contributes to chromosome instability, especially in p53-deficient cells. Here we show that an increase in intracellular reactive oxygen species (ROS) and oxidative DNA damage represents a major mechanism of Ras-induced mutagenesis. Introduction of oncogenic...
Background: The relationship between Coronary Artery Disease (CAD) and the prevalence of Renal Artery Stenosis (RAS) has been demonstrated. Despite high incidence of heart diseases and high frequency of CAD risk factors among Iranian population, this relation has not been clearly determined. This study estimated the prevalence of RAS and its determinants in Iranian angiographic candidates. We a...
BACKGROUND AND AIM: Recurrent aphthous stomatitis (RAS) is a lesion of the oral cavity with an unknown etiology. Several studies have been performed on the role of tumor necrosis factor-alpha (TNF-α) in RAS. The main purpose of this paper was to review TNF-α level and its gene polymorphism in patients with RAS, the factors influencing the production of TNF-α, a...
statement of the problem: recurrent aphthous stomatitis (ras) is one of the most common lesions in the oral cavity. due to its multifactorial nature, there is no definitive treatment for ras. laser therapy is one of the suggested treatments to reduce patient’s discomfort. purpose: the purpose of the present clinical trial is to assess the effect of low and high level laser therapy on pain contr...
OBJECTIVE To assess the frequency of adverse drug event (ADE)-related admissions (ADE-RAs) during a prospective medical record review of patients admitted to a metropolitan tertiary referral hospital. METHODS Potential ADE-RA cases were identified by examination of case records of randomly selected patients. Cases were assessed by an expert panel to measure study outcomes, which were the freq...
مقدمه: لوسمی حاد شایعترین بدخیمی کودکان است. یکی از مهم ترین عوامل ایجاد کننده لوسمی لنفوبلاستیک حاد(acute lymphoblastic leukemia) جهش های مربوط به پروتوانکوژنها و تبدیل آنها به انکوژن ها می باشد. از جمله این پروتوانکوژنها، پروتوانکوژن n-rasاست. از آنجایی که آماری از فراوانی جهش این ژن در کودکان all ایرانی وجود نداشت بر آن شدیم میزان فراوانی این جهش را در تعدادی از این بیماران بررسی و ارتباط ای...
Background: Ovarian carcinoma is one of the leading causes of cancer-related death among females. K-ras codon 12 mutations are commonly occurring mutations in different types of cancers and leads to resistance against anti-EGFR therapeutics. Hence, determination of mutations in k-ras gene is crucial for predicting response to anti-EGFR therapies. This study aimed to evaluate the prevalence of k...
Relationships between adenomatous polyposis coli (APC) mutations, BRAF V600E mutations, and the CpG island methylator phenotype (CIMP) in colon cancer have not been explored. In addition, controversies exist about the proportion of tumors with APC mutations in the mutation cluster region (MCR); how commonly APC, Ki-ras, and p53 mutations occur in the same tumor; and whether APC mutations occur ...
Rats exposed chronically to mild cold (5 degrees C/41 degrees F) develop hypertension and cardiac hypertrophy. This provides a unique model of hypertension that is environmentally induced. The blood renin-angiotensin system (RAS) has been shown to play a role in both initiating and maintaining the high blood pressure (BP) in cold-induced hypertension. The mechanism also appears to involve both ...
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