The rate of nucleic acid turnover is increased in malignant tissue, and hyperuricaemia and hyperuricaciduria may occur when the condition is widespread as in the myeloproliferative disorders and reticuloses. Patients who are undergoing treatment which involves the dissolution of large amounts of malignant tissue are at risk from acute urinary obstruction. This may be either intrarenal, through ...

The tetracyclines have enjoyed astonishing popularity since their introduction in 1950. They appeared to have many advantages over other preparations then in vogue and soon became known as 'broad spectrum' antibiotics, a euphemism which probably encouraged their widespread use as prophylactic agents for upper respiratory tract disease occurring in children (Banks, 1968; Banks and Ritchie, 1969)...

Submitted for the MAR09 Meeting of The American Physical Society Development of ferromagnetism in Pd nanoparticles with reduction in size MOHINDAR SEEHRA, JAMES RALL, West Virginia University, J. LIU, C. ROBERTS, Auburn University — Bulk fcc Pd is a paramagnet just missing the Stoner criterion for ferromagnetism (N(EF )I > 1) [1]. Several groups have reported weak ferromagnetism in 2-4 nm Pd na...

The pancreas forms from dorsal and ventral buds that appear at the foregut-midgut junction starting at embryonic day (E)9.5 in the mouse. Over the subsequent 10 days of fetal development, these two apparently uniform clusters of epithelial cells differentiate into the cell types that compose the adult pancreas: the endocrine cells of the islets of Langerhans, the duct cells, and the exocrine ce...

In normal conditions, serum (or plasma) iodine is largely composed of thyroxine and iodide with small quantities of thyroactive iodothyronines, such as 3: 5: 3'-tri-iodothyronine and 3: 3'-di-iodothyronine (Gross and Pitt-Rivers, 1952; Roche, Lissitzky, and Michel, 1952a and b; Roche, Michel, Nunez, and Wolf, 1956). Another relatively less active compound, 3: 3': 5'-tri-iodothyronine, is presen...

There is a major resurgence of interest in brown adipose tissue (BAT) biology, particularly regarding its determinants and consequences in newborns and infants. Reliable methods for non-invasive BAT measurement in human infants have yet to be demonstrated. The current study first validates methods for quantitative BAT imaging of rodents post mortem followed by BAT excision and re-imaging of exc...

During recent years the work of Sutherland and his associates (l-3) on the liver phosphorylase system has done much to clarify the mechanism of epinephrine-induced hyperglycemia. These workers have shown that epinephrine stimulates glycogenolysis by increasing the level of active phosphorylase in dog liver slices (3, 4) and in cell-free homogenates (5). The effect of epinephrine was shown to be...

Color correction describes the transformation process between device RGB values and CIEXYZ or CIELAB values. This mapping is in general not unique, because the spectral sensitivities of most of the devices do not satisfy the Luther condition and the acquisition and viewing light sources have a different power spectrum. Therefore, there exists a set of colors with different reflectance spectra w...

1. We used an in vivo preparation of the cat to study the passive cable properties of sixteen X and twelve Y cells in the lateral geniculate nucleus. Cells were modelled as equivalent cylinders according to Rall's formulations (Rall, 1959a, 1969, 1977). We injected intracellular current pulses into these geniculate neurones, and we analysed the resulting voltage transients to obtain the cable p...