Isolated intracranial hypertension is a common manifestation of intracranial sino-venous thrombosis (ISVT). Markedly elevated intracranial tension presents with unusual features including cranial neuropathies and radiculopathy. We report two cases with ISVT, which presented with headache, papilledema, progressive visual loss, complete ophthalmoplegia and flaccid areflexic quadriparesis along wi...

Permanent visual loss is a devastating yet preventable complication of cryptococcal meningitis. Early and aggressive management of cerebrospinal fluid pressure in conjunction with antifungal therapy is required. Historically, the mechanisms of visual loss in cryptococcal meningitis have included optic neuritis and papilloedema. Hence, the basis of visual loss therapy has been steroid therapy an...

background: in previous studies, the neuroprotective effect of 17&beta-estradiol; in diffuse traumatic brain injury has been shown. this study used ici 182,780, a non-selective estrogen receptor antagonist, to test the hypothesis that the neuroprotective effect of 17&beta-estradiol; in traumatic brain injury is mediated by the estrogen receptors. methods: the ovariectomized rats were divided in...

changes of intracranial pressure due to some curative and hygienic activities   a. mahmoodi rad msc1, m. foroozi msc2*, s. mohamad alizaheh msc3   1- academic member, school of nursing, lar, iran   2- academic member, school of nursing and midwifery, kerman, iran   3- academic member, school of nursing and midwifery, kerman, iran   background: evaluation the patients for determining the sings o...

When the brain is examined within a few days of injury it can be surprisingly difficult to establish what has been the cause of death, or to determine with certainty which lesions are primary and which are secondary, apart from clear-cut complications such as intracranial haematoma or infection. Recent reports of continuous measurements of intracranial pressure after head injury (Lundberg, Trou...

Tentorial herniation is caused by a pressure gradient between supra and infratentorial compartments and the herniated brain is burdened with a force, which is called shear strain at the edge of the tentorium. The purpose of the present study is to clarify the relationships between increased intracranial pressure, the pressure gradient and the tentorial shear strain. Twenty-three monkeys were us...

A patient presented with symptoms and signs of raised intracranial pressure and increasing focal deficit 13 months after stereotactic radiosurgical treatment of an arteriovenous malformation (AVM). Computed Tomography (CT) showed a mass lesion at the site of the previous abnormality typical of radiation necrosis, but with features identical to those of a malignant neoplasm. Biopsy confirmed cer...

With the prolongation of survival in patients with acute leukaemia the incidence of central nervous system involvement has shown a coincidental increase (Evans et al., 1970). Its actual frequency, however, remains difficult to estimate, for symptoms and signs may be minimal and meningeal leukaemia often occurs during bone marrow remission. Reports on patients with acute leukaemia and signs of r...

Idiopathic intracranial hypertension (IIH), a condition of raised intracranial pressure, is characterised by headaches and visual disturbances. Its pathogenesis is currently unknown; however, dysregulation of androgens may be implicated. Here, the authors present a case of a 22-year-old patient undergoing female-to-male (FTM) gender reassignment who developed IIH shortly after commencing testos...