Since the introduction of 3-dimensional conformal radiotherapy (3DCRT), new radiotherapy techniques have expanded the indication of radiotherapy for the treatment of hepatocellular carcinoma (HCC), from the hitherto palliative to a now curative-intent purpose. Intensity-modulated radiotherapy (IMRT), currently the most advanced radiotherapy technique, is considered an attractive option for the ...

Introduction: Ionizing radiation is non-surgical treatment of brain tumors and metastases. Preclinical studies have showed main insights into harmful effects of radiation on the nervous system in vivo and in vitro. Cognitive impairment such as progressive memory, executive and attention performance deficits indicates a significant risk for patients experiencing conventional rad...

Introduction: The present study evaluated the dosimetric comparison between 6MV flattened filter (FF) and flattening filter-free (FFF) photon beams in intensity-modulated radiation therapy (IMRT) technique for the treatment of glioblastoma (GBM) patients. Material and Methods: The present study was conducted on 10 patients with GBM previously...

The combination of radiotherapy (RT) and function-preserving surgery is the most usual contemporary approach in the management of soft tissue sarcomas (STS). Pre- and postoperative RT result in similar local control rates, as shown by a landmark trial in extremity STS. In this review, the role of RT in the management of extremity STS will be discussed, but STS in other sites, including retroper...

Submit Manuscript | http://medcraveonline.com Abbreviations: TCP: Tumor Control Probability; NTCP: Normal Tissue Control Probability; LKB: Lyman Kutcher Burman; IGRT: Image Guided Radiation Therapy; IMRT: Intensity Modulated Radiation Therapy; SIB-IMRT: Simultaneous Integrated BoostIMRT; VMAT: Volumetric Modulated Arc Therapy; DA: Double Arc; SA: Single Arc; HT: Helical Tomotherapy; IFP: Improv...

OBJECTIVE Various techniques are available for radiotherapy of hepatocellular carcinoma, including three-dimensional conformal radiotherapy, linac-based intensity-modulated radiotherapy and helical tomotherapy. The purpose of this study was to determine the optimal radiotherapy technique for hepatocellular carcinoma. METHODS Between 2006 and 2007, 12 patients underwent helical tomotherapy for...